Colonic diverticulosis has continuously increased, noticeably left-sided diseases, in Korea. A colovesical fistula is an uncommon complication of diverticulitis, and its most common cause is diverticular disease. Confirmation of its presence generally depends on clinical findings, such as pneumaturia and fecaluria. The primary aim of a diagnostic workup is not to observe the fistular tract itse...

Colonoscopy is a very usually diagnostic and therapeutic procedure in the diagnostic of colonic diseases. Most of the time it is secure procedure but complications can occur: hemorrhages (1.8-2.5%) and perforations (0.34-2.14%) are the most common. Others complications include pneumothorax, pneumediastinum, mesenteric tear and colonic volvulus [1,2]. Splenic rupture is a rare complication that ...

Osteogenesis imperfecta is a heterogeneous group of genetic disorders that affect the integrity of the connective tissue. Manifestations of the disease include bone fragility, osteoporosis, dentigenesis imperfecta, blue sclera, easy bruising, joint deformity and scoliosis. On the other hand, colonic diverticular disease is the most common acquired disease of the large bowel in the western popul...

Colonic epithelial health is implicated in a host of gastrointestinal (GI) diseases and disorders. Lysozyme is suspected to play a role in the ability of the epithelium to recover from injury (Abey et al., in press; Gallo, 2012; Rubio, 2014) [1], [2], [3]. Disrupted repair mechanisms may lead to delayed or ineffective recovery and disruptions to epithelial biology resulting in GI symptoms and a...

Inflammation is one of the major health threats to humans, and it associated with various chronic diseases, including metabolic syndrome, type 2 diabetes, cardiovascular several types cancer. For example, colonic inflammation can result in damage intestinal barrier, as indicated by invasion immune cells reduced tight junctions. Inflammatory responses also lead erythema edema on skin. The interv...

An 83-year-old male with a history of diabetes but with an otherwise intact immune system presented with melena. Upper endoscopy showed gastric and duodenal ulcers. Colonoscopy showed colonic ulcers. Biopsies revealed cytomegalovirus (CMV). Therapy with an antiviral such as ganciclovir should be considered even in an immunocompetent patient if male and over the age of 55, or if they have chroni...

Eosinophilic gastrointestinal diseases may affect the colon; however, isolated colonic involvement is very rare. Diagnosis of eosinophilic colitis requires clinical suspicion and it should be differentiated from other disorders causing eosinophil accumulation in the colon tissue. Herein we present a 46-year-old female admitted to the hospital with the complaints of bloody diarrhea (25-30 times ...

conclusions traf6 plays an important role in the onset of colon cancer; therefore, drugs targeting it may have great clinical significance in the treatment of this disease. results the positive expression rate of traf6 in tumor tissues was 66.7%, which was significantly higher than in normal paracancerous tissues (18.5%). the positive expression rate of traf6 was significantly correlated with d...

background: the incidence of colorectal cancer is rising in several developing countries. in the absence of integrated endoscopy and pathology databases, adenoma detection rate (adr), as a validated quality indicator of screening colonoscopy, is generally difficult to obtain in practice. we aimed to measure the correlation of polyp-related indicators with adr in order to identify the most accur...

Colonoscopy is a safe procedure for the diagnosis and management of colorectal diseases. Colonic perforation due to colonoscopy represents an uncommon complication. Here we present an unusual case of iatrogenic bowel perforation resulting in subcutaneous facial and neck emphysema, pneumomediastinum and pneumoretroperitoneum. Taking a detailed recent medical history information is always require...