BACKGROUND/AIMS Gastrointestinal and pancreatic neuroendocrine tumors (GEPNETs) originate from the cells of the endocrine system. Their molecular genetic mechanism of development and progression is complex and remains largely unknown. The purpose of this study was to review the gastrointestinal and pancreatic neuroendocrine tumors and to evaluate p53, Ki-67 and CD 117 expressions with their cli...

With less than 50 reported cases, gastrointestinal neuroectodermal tumor (GNET) is a rare malignant neoplasm. Here we report an unusual case of GNET with indolent clinical behavior. The patient is a 59-year-old Caucasian man whose 2 cm sigmoid colon mass did not increase significantly in size during a 10-year surveillance colonoscopy. This mass was recently resected due to change in bowel habit...

Introduction Sarcomatoid carcinoma (SC) is a rare subtype of malignant neoplasm with poor prognosis that involves both carcinomatous and sarcomatous components. Although it may develop in various organs, SC the large intestine has rarely been reported. It not for patients to have distant metastasis, reflecting its highly aggressive oncologic features, but cases brain metastasis on initial visit...

backgrounds and objectives: today we are witnessed a growing number of minimally invasive surgical techniques for different diseases. laparoscopic colon surgery as a minimally invasive surgery is currently growing in treatment of malignancies after proving his place in the treatment of benign diseases. we compare in this study results of laparoscopic colorectal surgery with open surgery. method...

a 12 year old child with liodgkin's disease and having received 12 courses of chemotherapy, was referred to thin center with esophageal obstruction. after having performed the necessary investigations, a decision was made to undertake surgery. after surgery, the patient recovered completely and presently enjoys a heallhv life.

background: routine screening colonoscopy is on the rise and pathologists have to deal with the ever larger numbers of excised colonic polyps. it is very important to optimize the patients’ individual treatment and further surveillance. pathologists play a critical role in management, as most of the clinical decisions concerning colonic polyp management are based on pathologic findings. one of ...

Chronic diarrhea is a symptom which persists for ≥ 4 weeks as of disease. often becomes the patient’s cause to be referred gastroenterology. In general, prevalence chronic approximated 5% in each populations, but there are obstacles diagnosing diarrhea, due many differential diagnoses diarrhea. The could neoplasm and non-neoplasm. several studies, through results colonoscopy histopathology, it ...

Introduction: Malignant peripheral nerve sheath tumor (MPNST) of the kidney is an uncommon neoplasm. We present a rare case MPNST successfully managed by surgical intervention. Case Presentation: A 23-year-old male patient presented with dull aching pain in right flank associated hematuria. On examination, abdominal mass firm consistency occupied lumbar quadrant fullness renal angle. Contrast-e...

The association between a multiple myeloma and a secondary solid tumor is not well established. Some reports showed an increased risk of secondary solid neoplasms in multiple myeloma patients, but others have not. Three cases of the synchronous occurrence of multiple myelomas and solid tumors, namely, a small cell carcinoma of the lung, an adenocarcinoma of the colon and a squamous carcinoma of...