نتایج جستجو برای: codon

تعداد نتایج: 20648  

Journal: :Nucleic Acids Research 1989

2017
Thomas Badet Remi Peyraud Malick Mbengue Olivier Navaud Mark Derbyshire Richard P Oliver Adelin Barbacci Sylvain Raffaele

The range of hosts that parasites can infect is a key determinant of the emergence and spread of disease. Yet, the impact of host range variation on the evolution of parasite genomes remains unknown. Here, we show that codon optimization underlies genome adaptation in broad host range parasites. We found that the longer proteins encoded by broad host range fungi likely increase natural selectio...

Journal: :The EMBO journal 2014
Dominique Chu Eleanna Kazana Noémie Bellanger Tarun Singh Mick F Tuite Tobias von der Haar

Synonymous codons encode the same amino acid, but differ in other biophysical properties. The evolutionary selection of codons whose properties are optimal for a cell generates the phenomenon of codon bias. Although recent studies have shown strong effects of codon usage changes on protein expression levels and cellular physiology, no translational control mechanism is known that links codon us...

Journal: :Molecular Biology and Evolution 2014

Journal: :Nucleic Acids Research 1986

Journal: :Trends in Evolutionary Biology 2012

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