Infectious mononucleosis (IM) is mostly caused by Epstein-Barr virus (EBV) while IM by cytomegalovirus (CMV) is rather rare. In our retrospective clinical research with multiplex virus PCR analysis, we encountered 6 cases of CMV-IM and analyzed the clinical characteristics including diagnostic problems. The diagnosis of CMV-IM was made when the CMV genome was solely detected from the patient’s ...

We report the frequency and type of infectious ocular complications following orthotopic liver transplantation (OLT) and review diagnostic and therapeutic strategies. During the period September 1988 through November 1994, 684 patients underwent OLT at Mount Sinai Hospital (New York). Nine orthotopic liver transplant patients (1.3%) developed ocular infections: Candida albicans endophthalmitis ...

BACKGROUND Due to underlying autoimmune background of Guillain-Barré syndrome (GBS), the possible role of infectious agents cytomegalovirus (CMV) and Epstein-Barr virus (EBV) and also due to association of anti-ganglioside antibodies with GBS, the present study aimed to investigate the associations between serum anti-ganglioside antibodies (AGA) level, type of infection and electrodiagnostic (E...

Acute Bacterial Meningitis in Guatemala City Daniel Olson, MD; James Gaensbauer, MD, MScPH; James Todd, MD; Neal Halsey, MD; Edwin J. Asturias, MD; Pediatric Infectious Diseases, University of Colorado Denver, Aurora, CO; Department of Infectious Disease, Children’s Hospital Colorado/University of Colorado School of Medicine, Aurora, CO; University of Colorado, Denver, CO; Johns Hopkins Bloombe...

Accurate and rapid diagnosis of human cytomegalovirus (HCMV) disease in immunocompromised patients has remained as a challenge. Quantitative competitive PCR (QC-PCR) methods for detection of HCMV in these individuals have improved the positive and negative predictive values of PCR for diagnosis of HCMV disease. In this study we used QC-PCR assay, using a co-amplified DNA standard, to quantitate...

147. An antibiotic stewardship program in the emergency department decreased piperacillin-tazobactam use and increased guideline-concordant antibiotic prescribing for uncomplicated cystitis Michelle Haas, MD; Bryan Knepper, MPH, MSc; Kevin Kaucher, PharmD; Kati Shihadeh, PharmD; Jeffrey Sankoff, MD; Timothy Jenkins, MD; Medicine/ Infectious Diseases, Denver Health Medical Center, Denver, CO; Me...

Human cytomegalovirus (HCMV) UL99-encoded pp28 is an essential tegument protein required for envelopment and production of infectious virus. Nonenveloped virions accumulate in the cytoplasm of cells infected with recombinant viruses with the UL99 gene deleted. Previous results have suggested that a key function of pp28 in the envelopment of infectious HCMV is expressed after the protein localiz...

The immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients initiating antiretroviral therapy (ART) results from restored immunity to specific infectious or non-infectious antigens. A paradoxical clinical worsening of a known condition or the appearance of a new condition after initiating therapy characterizes the syndrome. Potential mechanisms for the syndrome include a par...

This experimental study was carried out to induce a co-infection of H9 AIV and IBV with inoculumsprepared from tracheal scrubbed epithelium tissues in natural co-infected birds to rule out the effect of fieldundesired environmental conditions and also other infectious causative agents. Eighty 1-day-old broilerswere randomly divided into four equal groups. At 21 days of age, three test groups we...