نتایج جستجو برای: cns relapse

تعداد نتایج: 138293  

Journal: :The Journal of communicable diseases 2021

Introduction: Worldwide, Acute Lymphoblastic Leukaemia (ALL) is the most frequent cancer in children. One of major clinical challenges adequate diagnosis and treatment Central Nervous System (CNS) involvement this disease. CNS relapse has been a barrier to successful ALL for many years. Recent studies have shown encouraging results survival these patients long time. However, their long-term dep...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2013
H Holte S Leppä M Björkholm O Fluge S Jyrkkiö J Delabie C Sundström M-L Karjalainen-Lindsberg M Erlanson A Kolstad A Fosså B Ostenstad E Löfvenberg M Nordström R Janes L M Pedersen H Anderson M Jerkeman M Eriksson

BACKGROUND Many patients with aggressive B-cell lymphomas and high clinical risk score still die of lymphoma after conventional R-CHOP chemoimmunotherapy. We hypothesized that intensified chemoimmunotherapy including systemic central nervous system (CNS) prophylaxis improves outcome and reduces the incidence of CNS-related events. PATIENTS AND METHODS Inclusion criteria were age 18-65 years, ...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2007
V Boehme S Zeynalova M Kloess M Loeffler U Kaiser M Pfreundschuh N Schmitz

BACKGROUND Central nervous system (CNS) relapse is a devastating and usually fatal complication of aggressive lymphoma. The extent of the disease, the proliferation rate and the sites of extranodal involvement have been discussed as risk factors. We analyzed the patients treated on protocols of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL) between 1990 and 2000, evaluated th...

Journal: :Diagnostic microbiology and infectious disease 2013
Jonathan W Bush Terry Wuerz John M Embil Marc R Del Bigio Patrick J McDonald Sherry Krawitz

Blastomyces dermatitidis is a dimorphic fungus which is potentially life-threatening if central nervous system (CNS) dissemination occurs. Sixteen patients with proven or probable CNS blastomycosis are presented. Median duration of symptoms was 90 days; headache and focal neurologic deficit were the most common presenting symptoms. Magnetic resonance imaging (MRI) consistently demonstrated an a...

Journal: :Internal medicine 2008
Takaaki Konuma Jun Ooi Satoshi Takahashi Akira Tomonari Nobuhiro Tsukada Seiko Kato Senji Kasahara Kaoru Uchimaru Arinobu Tojo

A 32-year-old man 5 years previously received allogeneic bone marrow transplantation from his mother for Philadelphia chromosome positive acute lymphoblastic leukemia. He presented with headache, nausea, and pain in the left arm. The neurologic examination revealed no abnormalities except for stiffness of the neck. Gadolinium-enhanced T1weighted magnetic resonance imaging (MRI) showed diffuse c...

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