نتایج جستجو برای: clonal relationships
تعداد نتایج: 251828 فیلتر نتایج به سال:
Activation of naive T cells by quiescent APCs results in tolerance through deletion and anergy. The underlying basis for these distinct fates is unclear. Using clone 4 TCR transgenic animals as a source of naive CD8 T cells, we examined the requirements for peripheral deletion in vivo. Our results demonstrate that independent of the amount of Ag used for stimulation, a single dose was insuffici...
CD8+ T cell recognition of virus-infected cells is characteristically restricted by major histocompatibility complex (MHC) class I, although rare examples of MHC class II restriction have been reported in Cd4-deficient mice and a macaque SIV vaccine trial using a recombinant cytomegalovirus vector. Here, we demonstrate the presence of human leukocyte antigen (HLA) class II-restricted CD8+ T cel...
Clonal heterogeneity and selection underpin many biological processes including development and tumor progression. Combinatorial fluorescent protein expression in germline cells has proven its utility for tracking the formation and regeneration of different organ systems. Such cell populations encoded by combinatorial fluorescent proteins are also attractive tools for understanding clonal expan...
Abstract To evaluate the relationships among clones and open pollinated families from same plus trees to select elite breeding materials, growth, wood characteristics of 33-year-old Pinus koraiensis were measured analyzed. The results show that growth characters varied significantly. variation due clonal effects was higher than family effects. ratio genetic phenotypic coefficient in traits abov...
Clonal hematopoiesis can exist as both a driver and consequence of inflammatory dysregulation.
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