Cleft palate (CP) is one of the most common congenital malformations. It can occur as part of a recognisable syndrome, associated with other malformations or, most commonly, be non-syndromic (CPO) (MIM 119540). The birth prevalence of CPO varies between and among populations but it is seen world wide. The highest incidence has been found in Finland, 1.01 per 1000 livebirths. Within Finland, the...

Cleft is a congenital abnormal space or gap in the upper lip, alveolus, palate. This abnormality occurs between 5th and 10th weeks of pregnancy. Clefts are divided into cleft palate, as well lip palate caused by interaction individual genes with certain environmental factors. Mothers’ knowledge about risk factor may promote better health-related behavior their pregnancy increasing understanding...

BACKGROUND Alveolar and nasal reconstruction for patients with cleft lip and palate is a challenge for the reconstructive surgeon. Various procedures have been attempted to reduce the cleft gap so as to obtain esthetic results post surgically. Yet there is need of continuous exploration of newer and better methods. Rehabilitation of cleft lip and palate generally requires a team approach with p...

Mice models are an important way to understand the relation between the fetus with cleft palate and changes of maternal biofluid. This paper aims to develop a metabonomics approach to analyze dexamethasone-induced cleft palate in pregnant C57BL/6J mice and to study the relationship between the change of endogenous small molecular metabolites in maternal plasma and the incidence of cleft palate....

Cleft lip or palate is one of the most common types of craniomaxillofacial birth anomalies. Midface deficiency is a common feature of cleft lip and palate patients due to scar tissue of the lip and palate closure. Cleft lip and palate patients should be carefully evaluated by the craniofacial team in order to detect potentially serious deformities. Craniofacial team is involved with diagnosis o...

OBJECTIVE The purpose of this study was to investigate the distribution of different cleft patterns by sex, side of the cleft, and family history of clefts in a referral hospital in the south of Spain. STUDY DESIGN One hundred twenty-three consecutive cleft lip subjects, with or without palates, attending the Stomatology Unit in the Virgen del Rocío University Hospital and in the Virgen Macar...

OBJECTIVES Determination of the psychosocial status and assessment of the level of satisfaction in Malaysian cleft palate patients and their parents. DESIGN Cross-sectional study. PARTICIPANTS AND METHODS Sixty cleft lip and palate patients (12 to 17 years of age) from Hospital Universiti Sains Malaysia and their parents were selected. The questionnaires used were the Child Interview Schedu...

IN the past, the sporadic, unpredictable occurrence of cleft palate made the study of its embryological origins difficult. The discovery by Fraser et al. (1954) that large doses of cortisone injected into pregnant strain A/ Jax females would cause cleft palate in 100 per cent, of the offspring, provided a means for studying cleft palate in all stages of its development. Also, the lower incidenc...

purpose: to report a case of cloverleaf skull syndrome with cleft palate. results: we report a 20-day-old boy with cloverleaf-shaped skull deformity, very constricted cranium and prominent temporal bones associated with severe proptosis, maked lid retraction, conjunctival chemosis, exposure keratitis, corneal opacity and cleft palate. ct-scan dislosed fusion of the coronal, sagittal and lambdoi...