To give the Binkhorst Medal Lecture is without a doubt one of the greatest honors that can be bestowed on an ophthalmologist. Cornelius D. Binkhorst, MD, for whom the lecture was named, was a giant in our specialty. Having tried the IOL designed by Sir Harold Ridley soon after its development, Binkhorst realized that its main shortcomings related to its weight and its ability to remain stable i...

Replicated circular openings ranging in size from 0.1 to 1 ha were cleared on a Sierran mixed conifer forest in 1996 at the Blodgett Forest Research Station, California and planted with seedlings of six native species. After 3 years of growth, heights of all trees were measured and analyzed according to species, opening size, and location within the opening. To determine the cause of the edge i...

in this work, new biodegradable abcba type pentablock copolymers with different mole ratio of l-lactide and ppdo-b-peg-b-ppdo triblock copolymer were synthesized and characterized. in the first step, ppdo-b-peg-b-ppdo triblock copolymer was synthesized via a ring-opening polymerization of p-dioxanone (pdo) monomer with poly (ethylene glycol) (peg) using stannous octoate (sn(oct)2) as the cataly...

Recording simultaneously in vitro the changes of endoluminal pressure (index of circular muscle activity) and isometric tension (index of longitudinal muscle activity), we examined the mechanisms responsible for the apamin-sensitive relaxant and contractile responses induced by protease-activated receptor (PAR)-1 and PAR-2 activating peptides, SFLLRN-NH2 and SLIGRL-NH2, respectively, in rat col...

Introduction: SAR management is a widely discussed topic at main fields of 3T or above, particularly in the framework of multi-transmit systems [1,2]. Typically, local SAR is estimated via patient model simulations, i.e., extensive numerical calculations not suitable for clinical routine. An alternative way to estimate local SAR might be given by “Electric Properties Tomography” (EPT), i.e., th...

The successful use of continuous curvilinear (circular) capsulorhexis (CCC) in planned extracapsular cataract extraction (ECCE) is dependent on the feasibility of safe nuclear delivery through the smaller anterior capsular opening. Experimental evidence supports the proposition that the anterior capsular rim can stretch without tearing to dimensions which allow for safe nucleus delivery. Clinic...

A stereoselective synthetic route is reported for the introduction of side chains at the 3-position of trans-2-aminocyclopentanecarboxylic acid (ACPC). Ring opening of the aziridine 2-benzyloxymethyl-6-azabicyclo[3.1.0]hexane with selected nucleophiles occurs in a regioselective manner and provides ACPC precursors with functional groups at the 3-position, trans to the 2-amino group. Oligomers c...

We investigate the interaction of TbPc(2) single molecule magnets (SMMs) with ferromagnetic Ni substrates. Using element-resolved x-ray magnetic circular dichroism, we show that TbPc(2) couples antiferromagnetically to Ni films through ligand-mediated superexchange. This coupling is strongly anisotropic and can be manipulated by doping the interface with electron acceptor or donor atoms. We obs...

Mutation in the gene merry-go-round (mgr) of Drosophila causes a variety of phenotypic traits in somatic and germinal tissues, such as polyploid cells, metaphasic arrest, postmeiotic cysts with 16 nuclei, and spermatids with four times the normal chromosome content. The most characteristic phenotype is the appearance of mitotic and meiotic figures where all chromosomes are arranged in a circle....

The number of infrared beamlines at synchrotron facilities is expending worldwide. Due to the long wavelength of the radiation in the infrared region, the optimum collection of the emitted photons requires large opening angles, both vertically and horizontally (order of few tens of mrad). Most of the infrared beamlines use toroid shaped mirrors, or elliptical mirror to conjointly focus both the...