The purpose of this paper was to examine the validity and reliability of using photographs of wounds to accurately assess wound status. The results of assessing wound appearance using wound photographs was compared to results obtained from a bedside assessment using the Pressure Sore Status Tool (PSST). The photographic wound assessment tool (PWAT) used in this comparison represents a modified ...

The management of wound exudate requires the clinician to have an understanding of what it is, why it is present and how to monitor and assess it accurately (White and Cutting, 2006). Wound exudate was described as nature’s balsam many years ago (White and Cutting, 2006) and is the fluid produced by an open wound. It is derived from fluid that has leaked from capillaries into body tissues (Worl...

At any one time about 200,000 patients in the UK have a chronic wound, with the most common types of chronic wounds being leg ulcers, pressure ulcers and diabetic foot ulcers (Posnett and Franks, 2007). The cost to the NHS of caring for patients with chronic wounds is estimated to be about £4bn (Sheffield Hallam University, 2014). This cost is predicted to increase over the course of the next 2...

Objective: Many substances have been used for wound-burn treatment to date. Recent studies focused not only on covering the wound but also production of dressings that will provide patient comfort at highest level. This review mentions types and expected features an ideal dressing. An dressing should close protect against external factors such as microorganisms. It must appropriate absorption c...

Chronic wounds such as diabetic foot ulcers, venous ulcers, and pressure ulcers are a major source of morbidity and mortality. To describe wound characteristics associated with a wound emergency, the Wound Electronic Medical Records (WEMR) of 200 consecutive admissions (139 patients, average number of admissions 1.4) to a dedicated inpatient wound healing unit over a period of 5 months were ret...

Cutaneous wounds are among the most common soft tissue injuries and are particularly hard to heal in aging. Caloric restriction (CR) is well documented to extend longevity; pharmacologically, profound rejuvenative effects of CR mimetics have been uncovered, especially metformin (MET), resveratrol (RSV), and rapamycin (RAPA). However, locally applied impacts and functional differences of these a...

Introduction: Wound debridement is considered essential in chronic wound management. Hypochlorous acid has been shown to be an effective agent in reducing wound bacterial counts in open wounds. Ultrasound-enabled wound debridement is an effective and efficient method of debridement. This study compared ultrasound irrigation with hypochlorous acid versus saline irrigation for wound debridement o...

The sex hormones oestrogen and testosterone are important mediators of wound repair. Oestrogen enhances wound healing by reducing inflammation and enhancing matrix production. However, in post-menopausal women, when oestrogen levels are decreased, wound healing is impaired and susceptibility to chronic non-healing wounds increases. Surprisingly, although the speed of healing is impaired, an imp...

In the past, the genetically diabetic-obese diabetes/diabetes (db/db) and obese/obese (ob/ob) mouse strains were used to investigate mechanisms of diabetes-impaired wound healing. Here we determined patterns of skin repair in genetically normal C57Bl/6J mice that were fed using a high fat diet (HFD) to induce a diabetes-obesity syndrome. Wound closure was markedly delayed in HFD-fed mice compar...

correspondence: Linda S Higgins InteKrin Therapeutics, Inc, 4300 el camino real, Suite 201, Los Altos, cA 94022, USA Tel +1 650 941 5501 Fax +1 866 286 2242 email [email protected] Abstract: In healthy tissue, a wound initiates an inflammatory response characterized by the presence of a hematoma, infiltration of inflammatory cells into the wound and, eventually, wound healing. In pathological ...