renal failure by J. C. DUSSAULE, C. MICHEL, M. N. PERALDI, J. M. LECOMTE, C. GROS, F. MIGNON and R. ARDAILLOU Renal and systemic sympathetic counterregulation in response to vasodilators in renovascular hypertension by H. HERLITZ, P. HJEMDAHL, R. VOLKMANN, G. JENSEN and M. AURELL Plasma concentrations of immunoreactive-endothelin in patients with chronic renal failure treated with recombinant h...

Quadricuspid aortic valve is a rare congenital malformation of the heart leading to significant aortic regurgitation or stenosis. Its diagnosis by transthoracic echocardiography is difficult. Most of the cases are diagnosed during surgery or autopsy. Associated abnormalities of the coronary arteries should also be searched, since surgical injury may have devastating results. We herein present a...

In a 33-year-old patient with severe primary pulmonary hypertension, the acute administration of the angiotensin-converting-enzyme inhibitor captopril (SQ 14,225) induced a rise in cardiac output, and a fall in both pulmonary and systemic vascular resistance. Subsequent chronic oral administration of captopril induced only transient clinical improvement, and the patient died. Captopril may neve...

Chronic renal failure (CRF) is a common clinical problem in cats, affecting up to 30% of all animals above 15 years of age.1 Affected cats have a poor prognosis because the renal dysfunction frequently progresses to end-stage renal failure.2 The pathogenesis of CRF in general is not yet fully understood, but in people risk factors such as systemic hypertension, high dietary protein intake, and ...

A 34-yr-old man with hepatic haemangiomatosis presented for orthotopic liver transplantation. His massively distended abdomen caused thoracic compression and severe restrictive lung disease. Respiratory failure was the principal indication for transplantation. Increased airway pressures, pulmonary hypertension, systemic hypotension caused by aorto-caval compression, and blood loss, complicated ...

Correspondence to: Professor Marc Gewillig, Pediatric Cardiology, Gasthuisberg University Hospital, B 3000 Leuven, Belgium; marc.gewillig@ uzleuven.be _________________________ A normal mammal cardiovascular system consists postnatally of a double—pulmonary and systemic—circuit, connected in series, powered by a double pump—the ‘‘right’’ and ‘‘left’’ heart. Many complex cardiac malformations ar...

Background and Objective: Chronic Obstructive Pulmonary Disease (COPD) is a chronic obstructive and irreversible disease which has a high mortality and morbidity rate. Systemic inflammation and the thrombotic process can influence the prognosis of these patients. The objectives of this study were to evaluate prognostic effects of CBC indices (WBC, PMN, MPV, RDW), forced expiratory volume-one se...

T he interstitial lung diseases, like many chronic lung diseases, may lead to the development of pulmonary hypertension and cor pulmonale. The prevalence of pulmonary hypertension in these diseases is unknown, however. Current data suggest that prevalence varies with the type ofinterstitial disease.'3 In a group of patients with either idiopathic pulmonary fibrosis or interstitial lung disease ...

SARS-CoV-2 has driven the COVID-19 epidemic around world, making it one of most significant medical challenges last century. This infectious agent infects host cells by binding to ACE2 receptors (an enzyme present in several tissues, such as heart, lung and kidneys) can lead pneumonia, acute myocardial damage chronic cardiovascular system. Pre-existing conditions diabetes, hypertension obesity ...