Biofilm is the dominant form of skin microbiota organization that provides adhesion and preservation microorganisms in micro-environment. It necessary to ensure epidermal barrier function local immunomodulation. Staphylococcus aureus becomes major colonizer lesions case atopic dermatitis exacerbation, it also can biofilms. S. growth biofilm formation due other microbial commensals on patients w...

Blue Rubber Bleb Nevus Syndrome is a rare condition characterised bymultiorgan venousmalformations, in particular of cutaneous area and the gastrointestinal (GI) tract. We report here a child with chronic iron deficiency anaemia, melena and skin lesions. She had severe hypochromic microcytic anaemia. Upper and lower endoscopy revealed hundreds of red-bluish polypoid lesions involving the entire...

Abstract Crohn's disease (CD) is a chronic, relapsing, idiopathic condition, characterized by granulomatous, transmural inflammation of the gastrointestinal tract, which can affect its entire length, from mouth to anus. Metastatic (MCD) rare form skin involvement and defined lesions without contiguity with tract. A 9-year-old patient presented complaints gross in vulva perianal region. The diag...

Background. Eosinophilic dermatosis of hematologic disorders is a reactive process that may cause a variety of clinical manifestations. Methods. We report a patient who had outbreaks of skin lesions since the onset of chronic lymphocytic leukaemia. Results. The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions. Conclusion. We think that eosinop...

CD: Crohn’s disease INTRODUCTION Crohn’s disease (CD) is an idiopathic inflammatory bowel disease that is characterized by noncaseating granulomas that occur in the gastrointestinal tract. This disease is chronic, incurable, and prone to relapse. CD is frequently associated with skin and mucous membrane lesions. The skin is among the most common sites for extraintestinal involvement in CD. Esti...

Anti-tumor necrosis factor (anti-TNF) agents have been successfully used to treat both chronic idiopathic inflammatory bowel disease and other immune-mediated chronic diseases, but they can also induce a wide array of cutaneous reactions, including new-onset psoriasis and alopecia. We report a case of alopecia associated with psoriasiform skin lesions in a patient on adalimumab treatment for Cr...

Lymphomatoid papulosis, part of the controversial group of cutaneous lymphoproliferative pseudolymphoma disorders, raises important clinical and histopathological problems. It is a chronic, recurrent, clinically characterized by popular necrotic lesions and papulo-pustular nodules, sometimes self-limiting and characterized by histopathological changes suggestive of cutaneous lymphoma (CD30-posi...

Discoid lupus erythematosus (DLE) is a chronic skin disease that may affect the eyelids. Unless suspected, these lid lesions may resemble chronic blepharitis and persist for years. We present the clinicopathologic features of DLE from the lids of seven patients, electron microscopic features of one case, and a review of 31 previously reported cases.

Vulvar itching is a condition which frequently affects the women’s quality of life and can be quite disturbing, evenhindering their sleep. It has multifactorial origin, thus its management sometimes challenging. A goodhistory essential for making diagnosis. Equally important any similar history in spouse, family history, anyother GI symptoms, incontinence or other skin problems. Commonest cause...

To assess the consequences of oxidative stress in allergic and irritant contact dermatitis, we compared the iron level, unsaturated iron-binding capacity, total iron binding capacity, the percentage saturation of iron-binding capacity, the amount of diene conjugates as well as the amounts of total glutathione, reduced glutathione, oxidized glutathione, and the oxidized glutathione/reduced gluta...