Purpose: The present research evaluated the effect of using a back brace for 8 weeks on the Electromyography (EMG) activity of the selected muscles among individuals with chronic back pain in the mid-stance phase of walking. Methods: This quasi-experimental research evaluated 22 women with chronic back pain in terms of erector spinae muscles activity, abdominal erectus, abdominal external obli...

Chronic stimulation of a predominantly fast skeletal muscle enhanced the expression of type I (slow muscle) Ca-ATPase and suppressed the expression of the type II (fast muscle) Ca-ATPase. Monoclonal antibodies IID8 and IIH11 against type I (slow) and type II (fast) isozymes respectively, were used to type the Ca-ATPases of the isolated SR (sarcoplasmic reticulum) by Western blots, and the Ca-AT...

Peripheral muscle dysfunction is a common manifestation of advanced chronic obstructive pulmonary disease (COPD) and several other chronic diseases. Although the importance of this problem has been overlooked for several years, recent research indicates that peripheral muscle dysfunction may have important clinical consequences such as impaired functional status [1], poor quality of life [2], a...

de Frutos S, Nitta CH, Caldwell E, Friedman J, González Bosc LV. Regulation of soluble guanylyl cyclase1 expression in chronic hypoxia-induced pulmonary hypertension: role of NFATc3 and HuR. Am J Physiol Lung Cell Mol Physiol 297: L475–L486, 2009. First published July 10, 2009; doi:10.1152/ajplung.00060.2009.—The nitric oxide/soluble guanylyl cyclase (sGC) signal transduction pathway plays an i...

Epidemiological evidence suggests alcoholic myopathy is more severe in females than males, but comparable animal studies are lacking that make elucidating the biochemical locus for this defect problematic. The present study determined whether skeletal muscle protein synthesis and markers of degradation exhibit a sexual dimorphic response to either chronic alcohol consumption or acute intoxicati...

purpose: to evaluate the results of augmented vertical rectus muscle transposition with intraoperative botulinum toxin for complete and chronic sixth nerve palsy. methods: during a 10 years period (1381-1390) all patients with chronic and complete sixth nerve palsy, and contracted medial rectus (mr) underwent augmented vertical rectus muscle transposition with botulimum toxin injection into the...

The development of spinal hyper-reflexia as part of the spasticity syndrome represents one of the major complications associated with chronic spinal traumatic injury (SCI). The primary mechanism leading to progressive appearance of muscle spasticity is multimodal and may include loss of descending inhibitory tone, alteration of segmental interneuron-mediated inhibition and/or increased reflex a...

OBJECTIVE To estimate muscle metabolism and oxygen delivery to skeletal muscle in patients with chronic heart failure. METHODS 13 patients with chronic heart failure and 15 controls performed calf plantar flexion for six minutes at a constant workload of 50% of one repetition maximum. During recovery from exercise, skeletal muscle content of oxygenated haemoglobin (oxy-Hb) and the level of ph...