نتایج جستجو برای: chronic insomnia

تعداد نتایج: 506135  

2010
Andrew D. Krystal

1553 Efficacy and Safety of Doxepin in Elderly Insomnia Patients—Krystal et al INSOMNIA IS DEFINED AS DIFFICULTY INITIATING SLEEP, MAINTAINING SLEEP, AND/OR NONRESTORATIVE SLEEP ACCOMPANIED BY DAYTIME impairments.1 Although, not found in all studies, many investigations have found that the risk of insomnia increases with age.2-6 Insomnia has also been reported to be more severe in the elderly.2...

Journal: :medical journal of islamic republic of iran 0
mohammad abdollahi from the department of toxicology and pharmacology, tehran university of medical sciences naser jalali the poisoning and drug overdose ward, loghman-hakim hospita, shahid beheshti university of medical sciences, tehran, i.r. iran. amir ali jafari from the department of toxicology and pharmacology, tehran university of medical sciences

organophosphate chronic toxicity has been evaluated in this study. biological screening for organophosphate insecticide-exposed workers is mostly recommended for mixers, loaders, formulators and spraymen. we have studied 17 occupationally exposed persons to pesticides. using ellman's colorimetric method, their plasma cholinesterase activities have been measured. results show that the appea...

Journal: :Journal of psychosomatic research 2009
Børge Sivertsen Steinar Krokstad Simon Øverland Arnstein Mykletun

OBJECTIVE The aim of the present study was to examine the association of insomnia symptoms with demographic and physical and mental conditions in a large population-based study. METHODS Cross-sectional data on insomnia and comorbid conditions were gathered from 47,700 individuals aged 20-89 in Norway. Comorbid conditions included anxiety and depression and the following physical conditions: a...

Journal: :Archives of general psychiatry 2002
Daniel F Kripke Lawrence Garfinkel Deborah L Wingard Melville R Klauber Matthew R Marler

BACKGROUND Patients often complain about insufficient sleep or chronic insomnia in the belief that they need 8 hours of sleep. Treatment strategies may be guided by what sleep durations predict optimal survival and whether insomnia might signal mortality risks. METHODS In 1982, the Cancer Prevention Study II of the American Cancer Society asked participants about their sleep duration and freq...

Journal: :Sleep 2009
Alexandros N Vgontzas Duanping Liao Edward O Bixler George P Chrousos Antonio Vela-Bueno

STUDY OBJECTIVES To examine the joint effect of insomnia and objective short sleep duration on hypertension risk. DESIGN Representative cross-sectional study. SETTING Sleep laboratory. PARTICIPANTS 1,741 men and women randomly selected from central Pennsylvania. INTERVENTIONS None. MEASUREMENTS Insomnia was defined by a complaint of insomnia with a duration > or = 1 year, while poor s...

2016
Kai Spiegelhalder Wolfram Regen Christoph Nissen Bernd Feige Chiara Baglioni Dieter Riemann Jürgen Hennig Thomas Lange

Chronic insomnia is one of the most prevalent central nervous system disorders. It is characterized by increased arousal levels, however, the neurobiological causes and correlates of hyperarousal in insomnia remain to be further determined. In the current study, magnetic resonance spectroscopy was used in the morning and evening in a well-characterized sample of 20 primary insomnia patients (12...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2016
Rick Wassing Jeroen S Benjamins Kim Dekker Sarah Moens Kai Spiegelhalder Bernd Feige Dieter Riemann Sophie van der Sluis Ysbrand D Van Der Werf Lucia M Talamini Matthew P Walker Frans Schalkwijk Eus J W Van Someren

The mechanisms underlying hyperarousal, the key symptom of insomnia, have remained elusive, hampering cause-targeted treatment. Recently, restless rapid-eye-movement (REM) sleep emerged as a robust signature of sleep in insomnia. Given the role of REM sleep in emotion regulation, we hypothesized that restless REM sleep could interfere with the overnight resolution of emotional distress, thus co...

Journal: :Journal of Clinical Sleep Medicine 2020

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