helicobacter pylori was the main cause of gastric cancer (gc) in all over the world that results in intestinal- and diffuse-type carcinoma. infection by this bacterium remains chronic for a long time. in vitro studies have highlighted the role of stem cells in gc. h. pylori infection results in tissue injury and the adult/tissue stem cells subsequently start to replace the dead cells. the genet...

Objective To quantify an association between acute kidney injury and use of high potency statins versus low potency statins. DesignRetrospective observational analysis of administrative databases, using nine population based cohort studies and meta-analysis. We performed as treated analyses in each database with a nested case-control design. Rate ratios for different durations of current and pa...

introduction and aims: although a few studies have done in our country in the field of hepatitis d, its risk factors are not clearly known. this study was conducted with the aim of assessing the relative frequency and risk factors of hdv and the correlation between hdv and severity of liver damage. materials and methods: this was a cross sectional study. 280 hbsag positive subjects (including 1...

background:  to test the psychometric properties of the persian version of zarit burden interview (zbi-12) in the iranian opulation.  methods: after translating and cultural adaptation of the questionnaire into persian, 100 caregiver spouses of iran-iraq war (1980-88) veterans with chronic spinal cord injury who live in the city of mashhad, iran, invited to participate in the study. the persian...

OBJECTIVE To quantify an association between acute kidney injury and use of high potency statins versus low potency statins. DESIGN Retrospective observational analysis of administrative databases, using nine population based cohort studies and meta-analysis. We performed as treated analyses in each database with a nested case-control design. Rate ratios for different durations of current and...

BACKGROUND Musculoskeletal disorders of the lower extremities are commonly affected by chronicity and disability. One of the most commonly affected areas is the ankle. Epidemiological information is limited for chronic musculoskeletal ankle disorders in the general community, particularly in the developing world. This study aimed to determine the prevalence and impact of chronic musculoskeletal...

Ionizing irradiation induces acute and chronic injury to tissues and organs. Applications of antioxidant therapies for the management of ionizing irradiation injury fall into three categories: (1) radiation counter measures against total or partial body irradiation; (2) normal tissue protection against acute organ specific ionizing irradiation injury; and (3) prevention of chronic/late radiatio...

BACKGROUND Fibroblast growth factor-23 (FGF-23), a novel regulator of mineral metabolism, is markedly elevated in chronic kidney disease and has been associated with poor long-term outcomes. However, whether FGF-23 has an analogous role in acute kidney injury is unknown. The goal of this study was to measure FGF-23 levels in critically ill patients with acute kidney injury to determine whether ...

traumatic brain injury (tbi) is a global health concern that typically causes emotional disturbances and cognitive dysfunction. it elicits a complex secondary injury response, with neuroinflammation as a crucial central component. secondary pathologies following tbi may be associated with chronic neurodegenerative disorders and an enhanced likelihood of developing dementia-like disease in later...

Introduction. Chronic patellar tendon rupture (PTR) occurs rarely; its frequency and prevalence are unknown. There very little data on the late reconstruction in rheumatoid arthritis complications. Case report. We presented a surgical repair of PTR with early postoperative contralateral for 21-year-old woman past medical history juvenile (treated corticosteroids) who sustained initial injury 11...