introduction various types of dermatological manifestations have been reported due to hepatitis c virus (hcv) infection and anti­hcv therapy. some of them have been described during ifn-based therapies. peg-ifn-α-2a/rbv combination is used as the international standard of treatment for hcv infection for a long time. the combination therapy yields an adverse-event profile similar to standard int...

Among the large scope of extrahepatic manifestations related to hepatitis C virus (HCV) infection, many studies recently evaluated the frequency and characteristics of cardiovascular involvement. To assess the current published data on HCV infection and cardiovascular diseases. Published studies on cardiovascular disease, i.e. cerebrovascular accident and ischaemic heart disease in subjects wit...

BACKGROUND Fuyu city in China has a high prevalence of hepatitis C virus (HCV) infection resulting in a high morbidity and mortality from chronic liver disease and hepatocellular carcinoma. This study was conducted to identify the risk factors for HCV infection in Fuyu city. METHODS Recruitment of study subjects involved a cross-sectional survey using non-random, convenience sampling. Informa...

Context: Hepatitis C Virus (HCV) infection is a major cause of chronic cirrhosis and hepatocellular carcinoma. Approximately 30% infected persons with HCV spontaneously clear the viral infection; but, some remaining patients develop HCV. Studies show that HLA molecules play an important role in outcome by influencing efficiency antiviral immune response to infection. It now known polymorphisms ...

background and objectives: hepatitis c virus (hcv) infection is a worldwide concern and it is the major cause of liver disease. several genotypes of the hcv have been reported from different regions of the world. the determination of the hcv genotypes is important for the prediction of response to antiviral treatment and clinical outcomes. so, hcv genotyping in each region is of great importanc...

BACKGROUND/AIMS Helicobacter pylori infection causes gastritis, peptic ulcers and gastric malignancies, and its eradication has been advocated by many groups. We determined the H. pylori carrier status and eradication rates of patients with chronic hepatitis C virus (HCV) infection. METHODS In total, 76 chronically HCV-infected patients were enrolled for comparison with 228 HCV-noninfected, a...

Patients with chronic hepatitis C virus (HCV) infection frequently have many extrahepatic manifestations, as persistent HCV infection often triggers lymphoproliferative disorders and metabolic abnormalities. These manifestations primarily include autoimmune disorders such as cryoglobulinemia, Sjögren's syndrome, and autoimmune thyroid disorders. It has been well established that chronic HCV inf...

Hepatitis C virus (HCV) infection is the most common chronic bloodborne infection in the United States, with an estimated 3.9 million infected persons nationally and 85,000 persons infected in Wisconsin. HCV infection results in significant morbidity and mortality and contributes to high health care costs associated with specialized medical care, medications, and hospitalization. This report is...

AN Approximately 2.7 million (range, 2.2-3.2 million) Americans are estimated to be chronically infected with hepatitis C virus (HCV). This is the most-cited estimate based upon data from the National Health and Nutrition Examination Survey (NHANES). The majority of persons with chronic HCV were born between 1945 and 1965 (ie, baby boomers), and the peak incidence was in the 1970s and 1980s. A ...

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, which can lead to the development of liver cirrhosis and hepatocellular carcinoma. Current therapy of patients with chronic HCV infection includes treatment with IFNalpha in combination with ribavirin. Because most treated patients do not resolve the infection, alternative treatment is essential. RNA interference (RNAi...