Allergic contact dermatitis (ACD) of the hands can be a frustrating and underdiagnosed condition. While plant based products are a common source of ACD, tea leaves have rarely been reported as a cause of dermatitis. We describe a case of contact dermatitis from Pu-erh black tea as a result of chronic handling of tea leaves. Patch testing of both the patient and 6 normal controls helped to ident...

In diseases such as bronchial asthma or atopic dermatitis, which are based on a type II inflammation, biologicals part of the standard therapy. Since October 2019, bilogical dupilumab has been approved an add-on therapy for treatment severe chronic rhinosinusitis with nasal polyposis (CRSwNP). The aim this study is to evaluate acceptability, symptom development, and side effects after one year ...

Allergic contact dermatitis (ACD) is well recognized as an adverse event associated with implantable medical devices that contain allergenic materials like nickel; however, other cutaneous consequences of chronic exposure to allergens in implanted devices are not well understood. Here, we present a clinical case of Marjolin's ulcer, an invasive squamous cell carcinoma (SCC) that developed in re...

Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to thei...

Chronic contact hypersensitivity (CH) models induced by repeated hapten exposure exhibit chronic dermatitis and immunological abnormalities resembling atopic dermatitis. To assess the contribution of endothelial selectins (P- and E-selectins) to cutaneous chronic inflammation, chronic CH responses were assessed in mice lacking P- or E-selectin. Elicitation with oxazolone on the ears of P-select...

Atopic dermatitis is a common inflammatory skin disease, which most frequently occurred in children. The disease characterized as chronic, but only 20% of children have severe atopic dermatitis, while the other 80% achieve long-term remission by age 8. article summarizes main details about including statistical epidemiological data, signs course criteria for determining severity and aspects ste...

Atopic Dermatitis [AD] is a chronic relapsing inflammatory dermatological disease characterized by itch, dry skin, localized or disseminated eczematous lesions and hyperpigmentation of skin. There are several exogeneous endogenous risk factors for development AD. The include genetic factors, atopy, skin hyperreactivity such as food, dust, pollen, epidermal, fungal, bacterial, vaccine-associated...

Abstract Chronic actinic dermatitis (CAD) is characterized by a photoexposed site in association with objective evidence of photosensitivity, often arising on background atopic (AD). Dupilumab monoclonal antibody that inhibits signalling interleukin (IL)-4 and IL-13 licensed for the management moderate-to-severe AD. To date, nine case reports have suggested dupilumab can be clinically effective...