Background: The maternal age effect for trisomy is well known. However what is less established is whether certain women are more (or less) prone to segregation errors, independent of age. Trisomy arises primarily through maternal meiosis I chromosome segregation errors however the precise mechanism by which these errors occur is unclear. Current dogma attributes the origin of trisomy to malseg...

The West Virginia School of Osteopathic Medicine in Lewisburg instituted a free, community-based medical clinic in spring 1995 as part of an institution-wide Osteopathic Principles and Practices Integration Project. Under this initiative, osteopathic medical students are provided with 26 hours of supervised experience in osteopathic palpatory diagnosis and osteopathic manipulative treatment. Th...

BACKGROUND The National Board of Osteopathic Medical Examiners uses a standardized timing format for all osteopathic medical candidates across all stations in the Comprehensive Osteopathic Medical Licensing Examination-USA Level 2-Performance Evaluation (COMLEX-USA Level 2-PE). Examination standardization, and therefore validity, is weakened if time administered affects student performance. O...

Since its inception, osteopathic medicine has sought to identify the mechanical causes of disease and to understand the body's structure-function relationship. Research conducted during the past 25 years has demonstrated that the architectural principles of tensegrity can be applied to biological organisms (termed biotensegrity) and that these principles can demonstrate the mechanical structure...

the karyotype of zagros tooth-carp, aphanius vladykovi (coad) has been investigated byexamining metaphase chromosomes spreads obtained from gill epithelial and kidney cells. the diploidchromosome number of this species was 2n=48. the karyotype consisted of 8 submetacentric and 40subtelocentric chromosomes (8sm+40 st). the arm number (nf) was 28. sex chromosomes werecytologically indistinguishab...

background and objectives: primary amenorrhea is not a disease but a symptom that may result from several quite different causes[nn1] . common hormonal cause of primary amenorrhea includes constitutional delay, hypothalamic –pituitary dysfunction, chronic systemic disease and absent ovarian function. the aim of this study was to estimate the incidence of the chromosomal abnormality referred for...

CONTEXT The National Board of Osteopathic Medical Examiners uses the Osteopathic Manipulative Treatment (OMT) Global Rating Tool to score candidate performance in OMT during standardized patient encounters. To the authors' knowledge, no validity research has been published on the underlying constructs measured by this instrument to date. OBJECTIVE To evaluate whether the OMT Global Rating Too...

protein tyrosine phosphatases (ptpases) regulate the tyrosine phosphorylation of target proteins in volved in several biological activities including cell proliferation and transformation. protein tyrosine phosphatase e (ptpe) contains duplicated ptpase-like domains and a short extracellular region. us ing the fluorescence in situ hybridization method, the gene encoding ptpe (locus symbol ptpre...

Drimia is a heterogeneous, poorly understood genus that requires major rearrangement. Chromosome behavior of gigantea and viridula; two species in D. altissima complex was studied for karyotypes transmission extra chromosomes pair pollen viability. Meristematic cells at the root tips viridula were by conventional cytogenetic karyotype analysis. numbers 2n = 22 20 viridula, respectively. Extra c...