Abstract Study question What is the technical accuracy and clinical utility of reporting small copy number variants (CNVs below 3Mb) detected by a targeted next-generation sequencing-based PGT-A platform? Summary answer Some pathogenic or likely CNVs <3Mb can be accurately this assay, increasing for subset IVF patients. known already are linked to wide range phenotypes, spanning from syn...

AUTHOR Stenton, Jan TITLE Otitis Media: Implications of Fluctuating, Conductive Hearing Loss on Learning and Behaviour in High School Age Students. PUB DATE 1997-00-00 NOTE 16p.; Paper presented at the Annual Conference of the Australian Association for Research in Education (Brisbane, Australia, November 30-December 4, 1997). PUB TYPE Information Analyses (070) Reports Descriptive (141) -Speec...

AUTHOR Dail, Paula W.; Johnson, James E. 'TITLE Measuring Change in Undergraduate Student's Perceptions about Aging Using the Palmore Facts on Aging Quiz. SPONS AGENCY Wisconsin Univ., Madison. School of Family Resources and Consumer Sciences. PUB DATE Oct 83 NOTE 16p.; Paper presented at the Annual Meeting of the National Council on Family Relations (St. Paul, MN,, October 11-15, 1983). An ear...

Abstract A coincidence between the 2 S1/2–3 S1/2 two-photon transition in the atomic spectrum of 6Li and the X 1 + g → E 1 + g two-photon ro-vibrational series of Li2 was observed near 735 nm in a heat pipe oven using a tunable laser and thermionic diode detection scheme. The molecular transition obscures one component of the 6Li atomic transition. Selective detection of the atomic transition w...

Specific human papilloma virus (HPV) types appear to be necessary etiological factors for most cervical cancers, yet additional genetic alterations seem to be required for their development and progression. The aim of this study is to determine the likely chromosomes location of tumorigenicity suppressor-like genes, the loss of function of which might be important in the origin or progression o...

BACKGROUND MiR-133 expression is dysregulated in postmenopausal osteoporosis. However, its role in postmenopausal osteoporosis is still not well understood. In the current study, we explore how estrogen deficiency affects miR-133 expression and how miR-133 is involved in osteogenic differentiation of mesenchymal stem cells (MSCs). MATERIAL AND METHODS qRT-PCR analysis was performed to assess ...

Chromosomal defects are relatively frequent in infertile men however, translocations between the Y chromosome and autosomes are rare and less than 40 cases of Y-autosome translocation have been reported. In particular, only three individuals has been described with a Y;21 translocation, up to now. We report on an additional case of an infertile man in whom a Y;21 translocation was associated wi...