نتایج جستجو برای: cholesterol ester transfer protein
تعداد نتایج: 1585710 فیلتر نتایج به سال:
Cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol esters (CE) from atheroprotective high-density lipoproteins (HDL) to atherogenic low-density lipoproteins (LDL). CETP inhibition has been regarded as a promising strategy for increasing HDL levels and subsequently reducing the risk of cardiovascular diseases (CVD). Although the crystal structure of CETP is known, lit...
BACKGROUND We have searched if plasma high density lipoprotein-cholesterol (HDL-C) concentration interferes simultaneously with whole-body cholesterol metabolism and insulin sensitivity in normal weight healthy adult subjects. METHODS We have measured the activities of several plasma components that are critically influenced by insulin and that control lipoprotein metabolism in subjects with ...
This thesis is based on the following original articles, which are referred to in the text by their Roman numerals. metabolism in non-insulin dependent type 2 diabetics. cholesterol metabolism in obese type 2 diabetes. a new component of the metabolic syndrome: low cholesterol absorption. ABBREVIATIONS ABC adenosine triphosphate-binding cassette transporter ACAT acyl-CoA cholesterol acyltransfe...
The fact that a low level of high-density lipoprotein (HDL) cholesterol is highly predictive of future cardiovascular events has been established in population studies beyond all reasonable doubt. Furthermore, the evidence is overwhelming that the relationship is one of cause and effect rather than an epiphenomenon, with numerous studies in animals demonstrating that HDL-raising interventions t...
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