نتایج جستجو برای: chlorophenylalanine p

تعداد نتایج: 1269737  

Journal: :The Journal of pharmacology and experimental therapeutics 1999
A R Santos O G Miguel R A Yunes J B Calixto

The antinociceptive action of the alkaloid cis-8, 10-di-n-propyllobelidiol hydrochloride dehydrate (DPHD), isolated from Siphocampylus verticillatus, given i.p., p.o., i.t., or i.c.v., was assessed in chemical and thermal models of nociception in mice, such as acetic acid-induced abdominal constriction, formalin- and capsaicin-induced licking, and hot-plate and tail-flick tests. DPHD given by i...

2016
Danilo De Gregorio Luca Posa Rafael Ochoa-Sanchez Ryan McLaughlin Sabatino Maione Stefano Comai Gabriella Gobbi

d-lysergic diethylamide (LSD) is a hallucinogenic drug that interacts with the serotonin (5-HT) system binding to 5-HT1 and 5-HT2 receptors. Little is known about its potential interactions with the dopamine (DA) neurons of the ventral tegmental area (VTA). Using in-vivo electrophysiology in male adult rats, we evaluated the effects of cumulative doses of LSD on VTA DA neuronal activity, compar...

Journal: :The Journal of pharmacology and experimental therapeutics 1988
J F Nash H Y Meltzer G A Gudelsky

The racemic mixture of 3,4-methylenedioxymethamphetamine (MDMA), which has been reported to produce selective destruction of serotonergic neurons in the central nervous system, was studied to determine its neuroendocrine and temperature effects and mechanism of action. MDMA elevated serum concentrations of corticosterone in doses ranging from 3 to 20 mg/kg administered i.p. Serum corticosterone...

Journal: :The Journal of pharmacology and experimental therapeutics 2000
G L Mendes A R Santos A Malheiros V C Filho R A Yunes J B Calixto

Polygodial, a sesquiterpene isolated from the bark of Drymis winteri given systemically, intraplantarly, or by spinal or supraspinal sites, produced antinociception when assessed in both phases of the formalin test and against capsaicin-induced pain. Polygodial, even at high doses, had no antinociceptive or antihyperalgesic effect when assessed in hot-plate assay or in glutamate-induced hyperal...

Journal: :Journal of Neural Transplantation & Plasticity 1997
Ling Chen Kayoko Hamaguchi Shun Hamada Nobuo Okado

Previous studies in our laboratory [3,17] have demonstrated that serotonin (5-HT) appears to have a trophic-like effect in enhancing synapse formation and maintenance in both the developing and the adult central nervous system. In the present study, we focused on age-related changes in the density of the axosomatic and axodendritic synapses and the number of 5-HT-positive fibers in the chicken ...

2000
NEIL E. ROWLAND JONATHAN D. ROTH MEGAN R. MCMULLEN AASHISH PATEL ANNA T. CESPEDES

Rowland, Neil E., Jonathan D. Roth, Megan R. McMullen, Aashish Patel, and Anna T. Cespedes. Dexfenfluramine and norfenfluramine: comparison of mechanism of action in feeding and brain Fos-ir studies. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 278: R390–R399, 2000.—Dexfenfluramine (dF) and dexnorfenfluramine (dNF), its metabolite, are anorectic agents that release serotonin (5-HT) and...

2015
Dongxing Li Younju Lee Woojin Kim Kyungjin Lee Hyunsu Bae Sun Kwang Kim Sokcheon Pak

A single infusion of oxaliplatin, which is widely used to treat metastatic colorectal cancer, induces specific sensory neurotoxicity signs that are triggered or aggravated when exposed to cold or mechanical stimuli. Bee Venom (BV) has been traditionally used in Korea to treat various pain symptoms. Our recent study demonstrated that BV alleviates oxaliplatin-induced cold allodynia in rats, via ...

Journal: :British journal of pharmacology 1974
P B Bradley I Briggs

1 The actions of 5-methoxytryptamine (5-MeOT), N,N-dimethyltryptamine (DMT), 5-hydroxy-N,N-dimethyltryptamine (bufotenine, 5-HODMT) and 5-methoxy-N,N-dimethyltryptamine (5-MeODMT), and their interactions with 5-hydroxytryptamine (5-HT), acetylcholine, (-)-noradrenaline, and glutamate were studied by microiontophoresis on single neurones in the brain stem of rats anaesthetized with urethane or d...

رویا معلم سعید افشارزاده, سید جمال صاحبی شبنم عباسی غلامرضا بلالی

  با توجه کمبود اطلاعات درباره جنس Potamogeton در ایران و نیز با توجه به پراکنش گسترده آن در اکوسیستم­های آبی کشور، جمعیت های این جنس در اکوسیستم های مختلف اصفهان و چهار محال و بختیاری در طول رودخانه زاینده رود از نظر ریخت شناسی مورد بررسی قرارگرفت، برای این منظور نمونه برداری از 19 جمعیت این جنس انجام گرفت. در طی این مطالعه 6 گونه‌ی ,P. nodosus pusillus, P. perfoliatus, P. pectinatus, P. lucen...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بیرجند - دانشکده علوم ریاضی 1392

فرض کنید g گروهp-حل پذیر متناهی و p یک سیلوp- زیرگروه آن باشد. ثابت خواهیم کرد که اگر تمام اعضای p که مرتبه p هستند، مشمول در k-امین جمله از سری مرکزی بالایی p باشند، آن گاه p-طول g حداکثر m2+1 است، که در آن m بزرگترین عدد صحیحی است که .p^m-p^(m-1)?k

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