Reducing core temperature to protect the injured brain has become a new therapeutic measure. The scientific underpinnings based on animal experiments seem sound. Evidence of the therapy's effect in human trials is insufficient or even possibly absent, but the techniques to produce moderate hypothermia are available, without apparent significant complications, and are relatively easy to use for ...

Prostate cancer (PCa) is one of the most frequently diagnosed cancers in developed countries. Several studies suggest that variations in calcium homeostasis are involved in carcinogenesis. Interestingly, (Transient Receptor Potential Melastatin member 8) TRPM8 calcium permeable channel expression is differentially regulated during prostate carcinogenesis, thereby suggesting a potential function...

prospective studies of the potential health consequences of trade and investment treaties, such as the trans-pacific partnership, are critical. these studies can make visible to trade policy-makers the potential negative impacts associated to such treaties and can influence the outcomes of such negotiations. however, few researchers have examined retrospectively the consequences of trade agreem...

This article proposes and presents a novel approach to the characterization of winter precipitation and modeling of radar observables through a synergistic use of advanced optical disdrometers for microphysical and geometrical measurements of ice and snow particles (in particular, a multi-angle snowflake camera—MASC), image processing methodology, advanced method-of-moments scattering computati...

One of the methods used to surface hardening ductile iron is chilled cast iron. Chill as fast cooling rate in mold during solidification and chill thickness greatly affects hardness layer. The main material iron, SS 304. Casting uses sand casting method. Before pouring, plate has been inserted onto pattern that formed mold, then preheated at 700°C. Pouring was carried out a melting temperature ...