Introduction: Non-alcoholic fatty liver disease (NAFLD) is a clinical pathologic condition, which leads to inflammation events in hepatocytes. The objective of present study was to compare the plasma levels of VEGF and sVEGFR-1 as inflammation factors in overweight and obese children and adolescents with and without NAFLD. Materials and Methods: A total sample of 70 overweight and obese childre...

Hepatic masses constitute only 5% to 6% of all intra-abdominal masses in children (Pobeil & Bisset, 1995) and primary hepatic neoplasms constitute only 0.5% to 2% of all pediatric malignancies (Davey & Cohen, 1996). Primary hepatic neoplasms are the third most common abdominal malignancy in childhood, after Wilms’ tumor and neuroblastoma (Davey & Cohen, 1996). The majority of liver tumors in ch...

The aim of the study was to analyze the cohort of inpatient children with vascular anomalies according to the globally accepted classification introduced by the ISSVA. METHODS The study included 205 inpatient children within the time period of the years 2010-2015. Types of vascular anomalies (VAs), age of patients, diagnostic procedures, and anatomical localization of VAs were analyzed. RES...

OBJECTIVE Testicular adrenal rest tumours (TART) are a well-known complication in adult male patients with congenital adrenal hyperplasia (CAH), with a reported prevalence of up to 94%. In adulthood, the tumours are associated with gonadal dysfunction most probably due to longstanding obstruction of the seminiferous tubules. The aim of our study was to determine the presence of TART and their i...

Recent studies have resulted in major changes in the management of urinary tract infections (UTIs) in children. The present statement focuses on the diagnosis and management of infants and children >2 months of age with an acute UTI and no known underlying urinary tract pathology or risk factors for a neurogenic bladder. UTI should be ruled out in preverbal children with unexplained fever and i...

The aim of this study was to identify risk factors for neurological development in children aged 1 to 3 years with a mild paraparesis form of motor development of lower extremities. Identification and follow-up of the neurorisk factors is important for early detection of neurodevelopmental deviations as well as for initiating early therapeutic treatments, which can improve the processes of brai...

BACKGROUND: Obstructive variants of chronic duodenal obstruction may be caused by congenital malformations, such as rare periampullary duplication cysts. This localization gastrointestinal duplications is the rarest and not described in domestic literature.
 AIM: study aimed to present experience management cysts children.
 CASES REPORT: Seven children with underwent surgery between 2...

OBJECTIVE Osteopenia is a common complication of juvenile idiopathic arthritis (JIA). In adults, low bone density and increased fracture risk are associated with low vitamin K status of bone. The vitamin K-dependent protein osteocalcin plays an important role in bone metabolism. Its activity depends upon post-translational carboxylation in which vitamin K is an essential co-factor. Hence, vitam...