The Fos and Jun family of transcription factors contain an invariant sequence motif lysine-cysteine-arginine (KCR) in the highly conserved DNA-binding region. Reduction of the cysteine residue is necessary to facilitate DNA-binding. Here, we examined the potential dual roles of the flanking lysine and arginine residues in influencing the redox reactivity of the cysteine and the DNA-binding acti...

khanghah gilvan cemetery is located in khalkhal, in the iranian province of ardebil. this cemetery came into light during a highway construction project in khanghah village. until now, three archeological excavations, under the author’s supervision, have been carried out in this cemetery that has resulted in burials from the middle bronze age up to parthian period.   among the excavated burial...

The branch autonomy principle, which states that the growth of individual branches can be predicted from their morphology and position in the forest canopy irrespective of the characteristics of the tree, has been used to simplify models of branch growth in trees. However, observed changes in allocation priority within trees towards branches growing in light-favoured conditions, referred to as ...

Kinase suppressor of Ras (KSR) is a conserved component of the Ras pathway that acts as a molecular scaffold to promote signal transmission from Raf-1 to MEK and MAPK. All KSR proteins contain a conserved cysteine-rich C1 domain, and studies have implicated this domain in the regulation of KSR1 subcellular localization and function. To further elucidate the biological role of the KSR1 C1 domain...

Silver nanoparticles have gained considerable interest in recent decades due to their antimicrobial activity and are used water disinfection, wound healing, food packaging, plant protection. This study tested the potential of silver synthesized using neem (Azadirachta indica) leaf extract against Alternaria solani causes early blight disease tomato plants. The pathogen was isolated from infecte...

User mode program usually requires the assistance from hardware in order to execute a mode change before using system service. This also allows user mode program to gain complete control of hardware. In this paper, new instructions are proposed; the OS may then take advantage of these instructions to more effectively use the system service, while reducing the kernel size and adding to the flexi...

Generation of pluripotent stem cells (PSCs) in large domestic animals has achieved only limited success; most of the PSCs obtained to date have been classified as primed PSCs, which possess very little capacity to produce chimeric offspring. By contrast, mouse PSCs have been classified as naïve PSCs that can contribute to most of the tissues of chimeras, including germ cells. Here, we describe ...