Cancer and cardiovascular disease are the leading causes of death worldwide. Recent evidence suggests that these two life-threatening diseases share several features in progression, such as angiogenesis, fibrosis, immune responses. This has led to emergence a new field called cardio-oncology. Doxorubicin is chemotherapy drug widely used treat cancer, bladder breast cancer. However, this serious...

Background: Dilated cardiomyopathy (DCM) is revealed with the left ventricular dilatation and systolic dysfunction. This study was performed to determine the level of Calcitonin Gene Related Peptide (CGRP) and Brain Natriuretic Peptide (BNP) in children with dilated cardiomyopathy and controls and comparison of these two biomarkers in patients. Materials and Methods: This case-control study was...

Abstract Sarcomeric hypertrophic cardiomyopathy is among the most common genetic cardiovascular diseases.Clinical,electrocardiographic and echocardiographic evaluation plays a crucial role in diagnosis initial framing of phenotype. A 51–year–old Caucasian man with multiple myeloma,previous autologous transplant,undergoing chemotherapy for disease recurrence,without risk factors or family histor...

  Transient ischemic left ventricular dilation (TID) is a marker of severe and extensive coronary artery disease as well as an increased risk of adverse outcomes. The patients with more severe and extensive ischemia, multivessel-type of perfusion abnormality as well as patients with left anterior descending artery (LAD) territory perfusion abnormality have more probab...

      Right ventricular non-compaction cardiomyopathy (RVNC) is a genetic heterogeneous cardiomyopathy. Despite the increasing number of RVNC cases, the classification and natural history of this disorder are not completely clear. Also, because the pathogenic non-compaction cannot be easily differentiated from normal trabeculations, it is usually hard to accurately measure the prevalence of RV ...

we discuss here an uncommon condition of neurogenic hypotension in the context of immunoglobulin light chain (amyloid light-chain) amyloidosis. th e most serious feature was autonomic nervous system impairment, mainly characterized by severe refractory orthostatic hypotension, which became progressively invalidating, forcing the patient to bed. moreover, since the systemic involvement of the di...

during a period of four years between june, is, 1988 to june, is, 1992 one hundred and fourteen patients with congestive heart failure (chf) were admitted to the pediatric department of taleghani general hospital. during the above period, 192 patients with heart disease were hospitalized at this department and chf was the cause of admission in 59.4% of them. congenital heart disease (cho) was t...