The response of ISFETs (ion-sensltlve field-effect transistors) to concentrations of ions, especxally H+ ions, 1s determined by the type of gate surface Both the number of active surface sites and (proton) assoclatlon and dlssoclatlon constants influence the sensltlvlty In the case of a chemically-moddled gate surface, a new surface 1s formed, which generally has a different sensltlvlty It 1s s...

Multiple chemical sensitivity (MCS) or environmental illness has been the subject of numerous conferences (1,2), several research papers (3), and much controversy. What is the purpose of yet another workshop on this topic? Patients report that low-level chemical exposures are making them ill, yet these reports of illness are not well supported by the knowledge bases of toxicology or medicine. I...

Studies of unexplained symptoms observed in chemically sensitive subjects have increased the awareness of the relationship between neurological and immunological diseases due to exposure to volatile organic compounds (VOCs). However, there is no direct evidence that links exposure to low doses of VOCs and neurological and immunological dysfunction. We review animal model data to clarify the rol...

Nonlinear transport behaviors are crucial for applications in electronic technology. At the nonlinear critical turning point, the nonequilibrium states cause rich physics responses to environment. The corresponding study in this field is crucial for physics and industry application. Here nonlinear conductivity in charge-ordered (CO) LuFe(2)O(4 )has been demonstrated. Remarkable resistivity swit...

Knowledge representation was used to characterize beliefs in patients with Environmental Illness/Multiple Chemical Sensitivity (EI/MCS). EI/MCS patients, allergy and asthma patients, doctors and controls made relatedness judgments on concepts relevant to EI/MCS. Associative networks showed that EI/MCS patients viewed these concepts differently from others. Multiple chemical exposure was central...

There are nine well accepted paradigms of human disease. The tenth may explain the features of multiple chemical sensitivity (MCS) and a group of related illnesses including chronic fatigue syndrome (CFS), fibromyalgia (FM) and posttraumatic stress disorder (PTSD); Gulf War syndrome appears to be a combination of all four. The elevated nitric oxide/peroxynitrite vicious cycle paradigm explains ...

In the present work, the ZORA spin-orbit Hamiltonian, in conjunction with the gauge including orbital (GIAO) method based on DFT theory has been used to calculate 195Pt chemical shift of 195PtClxBr(6-x)(2-) complexes. Excellent agreement with experiments has been obtained for calculations bearing on optimized geometries and all electrons triple zeta + polarization (TZP) STO basis sets: the rela...

Transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (V1) perceive noxious temperatures and chemical stimuli and are involved in pain sensation in mammals. Thus, these two channels provide a model for understanding how different genes with similar biological roles may influence the function of one another during the course of evolution. However, the temperature sensitivity of TRPA...