BACKGROUND Clostridium difficile-associated disease (CDAD) is a serious nosocomial infection, however few studies have assessed CDAD outcome in the intensive care unit (ICU). We evaluated the epidemiology, clinical course and outcome of hospital-acquired CDAD in the critical care setting. METHODS We performed a historical cohort study on 58 adults with a positive C. difficile cytotoxin assay ...

OBJECTIVES To compare gender differences in the clinical expression of COPD patients attending a pulmonary clinic. MATERIALS AND METHODS We compared 53 FEV1-matched men and women with COPD attending a pulmonary clinic. We studied age, smoking pack-years history, Pa(O2), Pa(CO2), functional residual capacity, body mass index (BMI), dyspnea, 6-min walk distance (6MWD), health-related quality of...

BACKGROUND AND OBJECTIVES Dialysis patients are increasingly characterized by older age, multiple comorbidities, and shortened life expectancy. This study investigated whether the "surprise" question, "Would I be surprised if this patient died in the next year?" identifies patients who are at high risk for early mortality. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This prospective cohort ...

PURPOSE To compare the perioperative outcomes of laparoscopic partial nephrectomy (LPN) and robotic partial nephrectomy (RPN) for moderately or highly complex tumors (RENAL nephrometry score ≥ 7). MATERIALS AND METHODS A retrospective analysis was performed for 127 consecutive patients who underwent either LPN (n=38) or RPN (n=89) between 2007 and 2013. Perioperative outcomes were compared. ...

BACKGROUND The CHADS2 and CHA2DS2 scores are usually applied for stroke prediction in atrial fibrillation patients, and the Charlson comorbidity index (CCI) is a commonly used scale for assessing morbidity. The role in assessing mortality with score system in hemodialysis is not clear and comparisons are lacking. We aimed at evaluating CHADS2, CHA2DS2, and CCI scores to predict mortality in inc...

Comorbidities have considerable effects on survival outcomes. The primary objective of this retrospective study was to examine the association between age-adjusted Charlson comorbidity index (ACCI) score and postoperative in-hospital mortality in patients with digestive system cancer who have undergone surgical resection of their cancers. Using electronic hospitalization summary reports, we ide...

OBJECTIVES It was the aim of this study to determine the prognostic significance of the Charlson Comorbidity Index (CCI) following acute pulmonary embolism (PE) and assess the prognosis of patients without comorbidities (defined as a CCI score of 0). METHODS Outcomes of 1,023 consecutive patients admitted with confirmed PE were tracked after a median of 3.7 years (25-75th interquartile range ...

BACKGROUND Previous studies have provided the initial evidence for construct validity and test-retest reliability of the Mayo Hip Score. Instruments used for Total Hip Arthroplasty (THA) outcomes assessment should be valid, reliable and responsive to change. Our main objective was to examine the responsiveness to change, association with subsequent revision and the construct validity of the May...

La infección por SARS-CoV-2 en pacientes con cáncer puede ser severa y importante mortalidad. Diseñamos un estudio prospectivo observacional que tuvo como objetivo describir el impacto clínico epidemiológico de la tumores sólidos. Se incluyeron 27 neoplasias activas, una mediana edad 72 años, score Charlson 6. Las infecciones fueron adquisición nosocomial 18,5% los pacientes, 74% infiltrados pu...