Establishment of a productive HIV-1 infection in the female reproductive tract likely depends on the balance between anti-viral and pro-inflammatory responses leading to activation and proliferation of HIV target cells. Immune modulators that boost anti-viral and depress pro-inflammatory immune responses may decrease HIV-1 infection or replication. Polyinosinic:polycytidylic [Poly (I:C)] has be...

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The incidence rates of cervical adenocarcinoma have been increasing over the last two decades, contrary to those of squamous cell carcinoma. This trend is particularly evident among females aged <40 years and has occurred despite extensive cytology-based screening programs. The aim of the present retrospective database study was to investigate adenocarcinoma in situ (AIS) with respect to previo...

statement of the problem: the head and neck region is an uncommon site for metastatic involvement, but it can be the first and only symptom of primary cancer. the incidence of these tumors and their primary origins are limited in iranian patients. purpose: therefore, this retrospective study aimed to investigate the frequency and the common related clinical manifestations, as well as, the most ...

A 63-year-old man was evaluated for a 20-year history of dysphagia and vomiting. Barium-swallow esophagography showed Zenker's diverticulum at the upper end esophagus. Esophagogastroduodenoscopy revealed about 20 cm from incisors. There no mucosal inflammation or irregularity in diverticulum. Computed tomography that 8 size. lymphadenopathy around Because patient's symptoms were worsening, we p...

Background: Head and neck carcinoma is the malignant lesions which develops on lips, oral cavity, nasal mucosa, paranasal sinuses, inside or outside throat parotid glands. Magnetic resonance imaging can be a good alternative to invasive procedures for detection of metastatic disease in cases head tumors. Objective: To evaluate diagnostic accuracy magnetic detecting metastasis nodes squamous cel...

Human papillomavirus (HPV) is known to be associated with both cervical and oropharyngeal cancers, yet little are about the co-occurrence of similar HPV subtypes in these subsites. With changing sexual behaviour it necessary evaluate risk a woman abnormal cervix developing cancer oropharynx. A study evaluating infection oral mucosa therefore needed understand 2 different sites Oral wash specime...

Cervical agenesis is a rare clinical condition presenting with primary amenorrhea and often associated other Müllerian duct malformations. Quick definitive surgical treatment essential in preventing later, severe complications associating consequential endometriosis. The unsuccessful series of operations result loss the uterus. major challenge approaches not to reconstruct flow menstrual fluid ...

BACKGROUND RC-101 is a congener of the antiretroviral peptide retrocyclin, which we and others have reported is active against clinical HIV-1 isolates from all major clades, does not hemagglutinate, and is non-toxic and non-inflammatory in cervicovaginal cell culture. Herein, film-formulated RC-101 was assessed for its antiviral activity in vitro, safety in vivo, retention in the cervix and vag...

Mechanisms about regulation of mRNAs, microRNAs (miRNAs), and long non-coding RNAs (lncRNA) in cervical lymph node metastatic laryngeal squamous cell carcinoma (LSCC) remained unclear. Two sets of three microarrays of mRNA, miRNA and lncRNA in fresh surgical LSCC samples were established, respectively from three paired tumor and adjacent normal mucosa epithelial tissues in cN + (Positive metast...