CASE 1 Colin D. (generation E in Fig. 1), born on 9 September 1958, of non-consanguinous parents, was admitted to the Royal Hospital for Sick Children under the care of Professor R. W. B. Ellis in August 1960 with the complaint that since February of that year he had been increasingly unable to walk. The patient was the result of a full-term spontaneous delivery after an uncomplicated pregnancy...

Cerebro-cardiovascular disease (CVD) is one of compensable occupational diseases in Korea as in Japan or Taiwan. However, most countries accept only cardiovascular diseases (ischemic heart diseases) as compensable occupational diseases if any, but not cerebrovascular diseases. Korea has a prescribed list of compensable occupational diseases. CVD was not included in the list until 1993. In the e...

Nos. 3 and 4 worked in the same workshop. Nothing more definite than this could be ascertained. The symptoms were in all cases fairly typical, and the diagnosis easily established. A prominent feature was the rapid onset with high fever and restless delirium, followed by a period of depression of physical and mental powers. The temperature was mostly of an irregular type, while the pulse and re...

The first outbreak, or, at least the one of which any record exists, occurred in the year 1885. Subsequently, during the next decade, there were nine further outbreaks. After a cessation for three successive years, the fever broke out,for the eleventh time, at the latter end of 1898. There were three cases only, all occurring in the month of November between the 13th and the 26th. The mortality...

Cada vez más son los trabajadores que sufren el síndrome de Burnout, provoca estrés y ansiedad por motivos laborales con carácter crónico. De entre sus causas usuales, se encuentran hacer un trabajo necesite mucha energía o trabajar en ámbitos requieran atención. Por su parte, ámbito la Neurodidáctica, encarga conocer desarrollo del funcionamiento cerebro. Si aúnan atención a diversidad centros...

The clinical value of antiplatelet compounds strongly depends on the benefit-risk balance between their anti-thrombotic effects and the bleeding risk they incur. This ratio is especially important in the treatment of cerebro-vascular disease. Several novel compounds in clinical development hold promise to improve this benefit-risk ratio.

C erebral cavernous malformations (CCMs) are cerebro-vascular disorders with an approximate prevalence of 1 in 200. The CCM pathology is typified by abnormally dilated clusters of blood vessels with defective endothelial cell–cell junctions, sluggish blood flow, and almost always associated with hemosiderin deposition in the surrounding paren-chyma.

Clarifying the way in which the central nervous system (CNS) controls motor behavior is an area of ongoing investigation in biology and medicine. Many of the neurophysiological details of how even the simplest voluntary movements are organized and executed remain to be established. Part of the motivation is basic scientific interest in achieving a better understanding of the brain, spinal cord ...