Subjective visual experience leaves two distinct, overlapping 'footprints' within visual cortex: a small 'footprint' evident in multi-unit activity, and a much larger 'footprint' that dominates activity indexed by haemodynamic responses.

Fifty three children aged 6 years old who had weighed less than 1251 g at birth without cerebral palsy and receiving mainstream education, were entered into a controlled study of motor skills. The index and control children were matched by age, sex, and school. The index group were considered by their teachers to have similar academic performances to their index group were considered by their t...

Aging is associated with a number of degenerative changes in the structure and function of blood vessels. Recent studies have examined the impact of age on cerebral hemodynamics and brain structure and function. These studies have shown age related changes in resting cerebral blood flow, cerebral vasoreactivity, cerebral autoregulation, and neurovascular coupling. Studies have also shown that a...

The validity of using transcranial Doppler measurement of cerebral blood flow velocity (CBFV) to assess cerebral autoregulation (CA) still is a concern. This study measured CBFV in the middle cerebral artery using transcranial Doppler and volumetric cerebral blood flow (CBF) in the internal carotid artery (ICA) using color-coded duplex ultrasonography to assess CA during steady-state changes in...

CYTOCHROME OXIDASE (CYTOX) IS A MITOCHONDRIAL ENZYME THAT IS RESPONSIBLE FOR THE FINAL METABOLISM OF MOLECULAR OXYGEN TO PRODUCE ADENOSINE TRIPHOSPHATE (ATP) IN THE RESPIRATORY CHAIN. Because its absorption spectrum changes between the oxidized and reduced state, the concentration of the oxidized form can be monitored using near-infrared spectroscopy (NIRS).1 This provides a unique method of im...

Effects of Alpha Adrenergic Blockade on Autoregulation and Chemical Vasomotor Control of CBF in Stroke • Autoregulation and chemical vasomotor control of cerebral blood flow (CBF) were quantitatively tested in 19 patients with various types and sites of cerebral ischemia and infarction. The effect of alpha adrenergic blockade of cerebral vessels by phenoxybenzamine (PBZ) also was evaluated in m...

Many doctors involved in the critical care of head-injured patients understand intracranial pressure (ICP) as a number, characterizing the state of the brain pressure-volume relationships. However, the dynamics of ICP, its waveform, and secondarily derived indices portray useful information about brain homeostasis. There is circumstantial evidence that this information can be used to modify and...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 cerebral amyloid angiopathy (caa) is the most common cause of lobar intracerebral hemorrhage. repeated bleeding may be presented with vascular dementia. we have reported a 68-year-old normotensive demented patient with probable caa presented with hemiparesia, headache and vomiting. according to the experience of this case,...

BACKGROUND AND PURPOSE Although cerebral circulation time (CCT) is one of the main parameters in cerebral blood flow measurements, its clinical significance is controversial. To assess the importance of CCT by using a nondiffusible indicator, we studied the relationship between angiographic CCT and cerebrovascular reserve. METHODS Twenty-eight patients, each with a unilateral occlusive lesion...

BACKGROUND AND PURPOSE Homocystinuria due to cystathionine beta-synthase deficiency and familial hypercholesterolemia are inherited disorders of metabolism that are associated with premature development of cardiovascular disease. This study addresses the possibility that different patterns of carotid wall damage and cerebral blood flow hemodynamics are present in these two metabolic diseases. ...