Actinic granuloma is a rare, idiopathic disorder of middleaged adults that always appears in sun-exposed skin [1,2]. It is a form of granulomatous dermatosis characterized by annular plaques with central atrophy and raised erythematous margins that are similar to those observed in granuloma annulare (GA) [3]. A 42-year-old man presented with a three-month history of an asymptomatic erythematous...

OBJECTIVE This study investigated whether some components of the extracellular matrix and CD68 expression may drive the differences between the central giant cell granuloma (CGCG) of the jaws and giant cell tumor (GCT) of long bones, which present distinct evolution and clinical behavior. MATERIAL AND METHODS Eight cases of CGCG and 7 cases of GCT were selected and immunohistochemically analy...