background: numerous evidences indicate that in some hiv-1 positive patients, the humoral and cellular immune responses are induced against hiv-1 proteins and this is inversely related to the progress of infection. objective: the aim of this study was the evaluation of the adenovectors containing hiv genes in induction of immune responses in mice. methods: the hiv-1 genes including gag p24, rev...

parkinson’s disease (pd) is the second most common neurodegenerative brain disorder which is around 1.5 times more common in men than in women. currently, drug medications, surgery, and lifestyle changes are common approaches to pd, while all of them focused on reducing the symptoms. therefore, regenerative medicine based on stem cell (sc) therapies has raised a promising hope. various types of...

the eukaryotic complexity involves the expression and regulation of genes via rna-dna, rna-rna, dna-protein and rna-protein interactions. recently, the role of rna molecules in the regulation of genes in higher organisms has become more evident, especially with the discovery that about 97% of the transcriptional output in higher organisms are represented as noncoding rnas: rrna, snornas, trna, ...

fitzhugh-nagumo (fhn) model is a famous reaction-diffusion system which first introduced for the conduction of electrical impulses along a nerve fiber. this model is also considered as an abstract model for pattern formation. here, we have used the cellular automata method to simulate the pattern formation of the fhn model. it is shown that the pattern of this model is very similar to those of ...

urban settlements and their connectivity will be the dominant driver of global change during the twenty-first century. in an attempt to assess the effects of urban growth on available land for other uses and its associated impacts on environmental parameters, we modeled the change in the extent of gorgan city, the capital of the golestan province of iran. we used landsat tm and etm+ imagery of ...

abstract this paper presents a multiobjective power control algorithm that updates the transmitted power based on local information. the proposed algorithm is expanded by using multiobjective optimization schemes. the objectives to be optimized in this paper are determined so as to reduce the sinr fluctuations as well as maintaining the sinr to an acceptable level with minimizing an average tra...

it is shown in [1] that the optimal downlink radio resource allocation for non-realtime traffic in cellular cdma/tdma networks can be mapped to a multi-dimensional multiple-choice knapsack problem (mmkp) which is np-hard. in this correspondence we propose a heuristic algorithm with polynomial time complexity for this problem. numerical results indicate significant computational performance impr...

Background: The incidence of diabetes mellitus is rapidly increasing in the world. One of the complications of diabetes includes disturbance of the reproductive tract, such as infertility, erectile dysfunction, and endocrine disturbances. Nitric oxide (NO) is a free radical produced by most of cells including the human male and female reproductive tracts. NO has a dual role where low concentrat...

Lipid nanocapsules (LNCs) represent a stable, biocompatible and worthwhile drug delivery system, demonstrating significant potential as gene/drug delivery platforms for cancer therapy. Imatinib, a potent tyrosine kinase inhibitor, has revolutionized the therapy of malignancies resulting from abnormal tyrosine kinase activity. However, its Clinical effectiveness in cancer treatment is h...

Lipid nanocapsules (LNCs) represent a stable, biocompatible and worthwhile drug delivery system, demonstrating significant potential as gene/drug delivery platforms for cancer therapy. Imatinib, a potent tyrosine kinase inhibitor, has revolutionized the therapy of malignancies resulting from abnormal tyrosine kinase activity. However, its Clinical effectiveness in cancer treatment is h...