Excessive apoptosis of intervertebral disk cells and degeneration (IDD) is the prime cause low back pain. B-cell lymphoma 2 (Bcl-2) adenovirus E1B 19 kDa interacting protein 3 (BNIP3), a member Bcl-2 family, are involved in cell autophagy apoptosis. The roles mechanisms BNIP3 unclear. In this study, primary rat were prepared to study effect overexpression on their counting kit (CCK)-8 assay sho...

objective(s): the periodic binding of protein expressed by mycobacterium tuberculosis h37rv with the host cell receptor molecules i.e. fibronectin (fn) is gaining significance because of its adhesive properties.  the genome sequencing of m. tuberculosis h37rv revealed that the proline-glutamic (pe) proteins contain polymorphic gc-rich repetitive sequences (pgrs) which have clinical importance i...

background: this study was performed to induce conversion of rh strain tachyzoites of toxoplasma gondii to bradyzoites by ph changing of the cul­ture medium. methods: hela cell monolayers were infected at a 1:1 tachyzoite to cell ratio. four hours after infection, the culture medium was removed and re­placed with culture medium and 5% fcs, adjusted to ph 8 with naoh. the culture was maintained ...

Experiments and theoretical modeling show that disassembly of vimentin intermediate filaments---a key process in many biological cell functions---proceeds via filament breakage without the assistance other proteins.

seed storage proteins are synthesized as sources of carbon, nitrogen and sulfur for the next generation of plants. reactive oxygen species serve as second messengers for signal transduction; however, molecular targets of oxidant signaling have not been defined. here, many researchers showes that ligand–receptor mediated signaling promotes reactive oxygen species– dependent protein carbonylation...

Cell to communication is the most important process in all living organisms. This network essential for growth, differentiation, development and metabolic functions. As plant cell has a rigid wall so there are some special ways using through structure called Plasmodesmata. The messages from DNA of dividing cells pass signals or other RNA molecules. But molecules cannot independently cells, prot...

Microplasts are large extracellular vesicles originating from migratory, invasive, and metastatic cancer cells. Here, to gain insight into the role of microplasts in progression, we performed a proteomic transcriptomic characterization isolated MCF-7 breast cells treated with macrophage-conditioned medium. These were found be viable, highly metabolically active, indicating that derived these no...