We report a rare case of double primary lung carcinoma including large cell neuroendocrine carcinoma (LCNEC). A 67-year-old man underwent an annual medical checkup in 2000, pulmonary carcinoma was strongly suspected by sputum cytology and radiological images. Preoperative diagnosis was double primary lung carcinoma with a squamous cell carcinoma in the right lower lobe and non-small cell carcin...

Time Trends in Lung Cancer Incidence Susan Devesa (National Cancer Institute) presented lung cancer incidence data for the period 1969-i986 for five geographic areas (Atlanta, GA; Connecticut; Detroit, Ml; Iowa; San Francisco, CA; and Oakland, CA) covering 7% of the United States population. Overall, the rate of lung cancer increased 3%/year from 38.6 to 58.4/1 00,000 personyears during this pe...

Background: Lung cancer most common worldwide cancer, early diagnosis makes effective treatment in lung cancer. Liquid Based Cytology (LBC) for non-gynae specimens has gained popularity over conventional Cytology (CS) during last one decade because of increased sensitivity and specificity. Aim and objectives: To assess the diagnostic utility of LBC versus CS in fine needle aspirates of lung and...

The aim of the present study was to analyze the stem cell marker, Nanog gene, for the diagnosis and prognosis of lung cancer cases, and to study its application in the diagnosis of lung cancer. In total, 100 patients diagnosed with lung cancer between April, 2013 and May, 2015 were included in the present study. The patients were randomly divided into group A (lung cancer) and group B (squamous...

Cancer is considered as a challenging deathly disease and discovering or synthesis of new cytotoxic agents is a worldwide attempt. In this study, a group of recently synthesized chalcones, with the structure of 1,3-diarylprop-2-en-1-one having differesnt COX-1 and/or COX-2 selectivities, have been examined on human hepatocarcinoma (HepG2), lung carcinoma (A549), and breast adenocarcinoma (MCF-7...

Cancer is considered as a challenging deathly disease and discovering or synthesis of new cytotoxic agents is a worldwide attempt. In this study, a group of recently synthesized chalcones, with the structure of 1,3-diarylprop-2-en-1-one having differesnt COX-1 and/or COX-2 selectivities, have been examined on human hepatocarcinoma (HepG2), lung carcinoma (A549), and breast adenocarcinoma (MCF-7...

this case series reports 100 patients with lung cancer and their presenting neurologic symptoms and sings. 78% of patients were maleand 22% were female. mean age was 62±1.04 years with a peak age between 65 and 75 years. most patients presented with pulmonary problems (58%) and neurologic deficits as the presenting manifestations were found to be 30% along with pulmonary symptoms and 12% laking...

Primary liver cancer is characterized by closely related with chronic inflammation, thereby reversing hypoxic immunosuppressive microenvironment of tumor cell growth immunotherapy drug a potentially effective strategy. Camrelizumab an anti-PD-1 antibody being developed Jiangsu Hengrui Pharmaceuticals Co., Ltd. We reported case adult critical Chinese patient primary hepatocellular carcinoma and ...

PURPOSE The peroxisome proliferator-activated receptor gamma (PPARgamma), a ligand-dependent transcription factor belonging to the family of nuclear receptors, has been implicated in the regulation of cell growth and differentiation although the exact mechanism(s) of this activity has not been elucidated. In this study, we explored the role of PPARgamma signaling on the control of gene expressi...

Purpose: The peroxisome proliferator-activated receptor (PPAR ), a ligand-dependent transcription factor belonging to the family of nuclear receptors, has been implicated in the regulation of cell growth and differentiation although the exact mechanism(s) of this activity has not been elucidated. In this study, we explored the role of PPAR signaling on the control of gene expression of the cycl...