The asymmetric unit of the title compound, 2K(+)·2C(6)H(7)N(2)O(2)S(-)·3H(2)O, consists of two potassium cations located on mirror planes, one sulfanilamidate anion in a general position and one and a half mol-ecules of water, one of which is also located on a mirror plane. One potassium cation is seven-coordinated by six sulfonyl O atoms and one water mol-ecule, whereas the other is surrounded...

The title compound, [SnBr(4)(H(2)O)(2)]·3H(2)O, forms large colourless crystals in originally sealed samples of tin tetra-bromide. It constitutes the first structurally characterized hydrate of SnBr(4) and is isostructural with the corresponding -hydrate of SnCl(4). It is composed of Sn(IV) atoms octa-hedrally coordinated by four Br atoms and two cis-related water mol-ecules. The octa-hedra exh...

Copyright: © 2013 Chitlange SS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Stability-Indicating HPTLC Method for Simultaneous Estimation of Amoxicillin Trihydrate and Ambroxol Hydrochloride in Bulk...

BACKGROUND Neisseria gonorrhoeae can rapidly develop resistance to antimicrobial agents. Over the last years, decreased gonococcal susceptibility to third-generation cephalosporins, especially cefixime, emerged worldwide. Therefore, current international guidelines recommend dual therapy for gonorrhoea with ceftriaxone plus either azithromycin or doxycycline. Gonococcal susceptibility data in S...

We conducted a systematic review and meta-analysis of ceftriaxone for treatment of uncomplicated gonorrhoea compared with four other antibiotics. Thirteen randomized controlled trials (RCTs) totalling treatment of 2557 patients with uncomplicated gonorrhoea were included. Statistically significant differences were observed in side-effects, which were increased after ceftriaxone 250 mg versus ce...

Commentary Background Reports of a gonorrhoea 'superbug' made the headlines last year following the description of a ceftriaxone-resistant i solate of Neisseria gonorrhoeae. 1 But is antimicrobial resistance a significant problem and what is the current reality of N. gonorrhoeae infection in the UK? Is gonorrhoea getting meaner? Anogenital infection with N. gonor-rhoeae has been highly responsi...

Among gonococcal isolates examined at the Hawaii State Laboratory Division from 2003 to 2011, the prevalence of elevated cefixime minimum inhibitory concentrations (MICs; ≥0.064 μg/mL) and elevated cefpodoxime MICs (≥0.19 μg/mL) increased over time. In contrast, few isolates exhibited elevated ceftriaxone MICs (≥0.094 μg/mL), and the prevalence of elevated ceftriaxone MICs did not change.