Chronic hepatitis C virus (HCV) infection causes substantial morbidity and mortality in the United States. Testing and treatment of asymptomatic persons might avert progression to more advanced disease. In 1998, CDC published guidelines for HCV testing based on risk factors for infection; however, recent studies indicate that at least one half of all persons living with HCV infection in the Uni...

Cri du Chat syndrome (CdC) is a chromosomal abnormality (deletion of short arm of chromosome 5) associated with intellectual disability and typical anatomical abnormalities. Research up to now focuses on the management of the disease during childhood. The longer lifespan of these patients warrants deeper investigations of how and if aging could be affected by the syndrome. We decided to focus o...

BACKGROUND  Preexposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine (Truvada) has demonstrated efficacy in placebo-controlled clinical trials involving men who have sex with men, high-risk heterosexuals, serodiscordant couples, and intravenous drug users. To assist in the real-world provision of PrEP, the Centers for Disease Control and Prevention (CDC) has released ...

May 19–25, 2014, marks the 10th annual Recreational Water Illness and Injury Prevention Week. This observance highlights ways in which swimmers, parents, pool owners and operators, beach managers, and public health can maximize the health benefits of water-based physical activity, while avoiding water-associated illness and injury. To help keep swimming a healthy and safe activity, CDC has rece...

The Hospital Infection Control Practices Advisory Committee of the US Centers for Disease Control and Prevention and the National Center for Infectious Diseases have issued new isolation guidelines that replace earlier recommendations. Modifications of these guidelines for the care of hospitalized infants and children should be considered specifically as they relate to glove use for routine dia...

These competency guidelines outline the knowledge, skills, and abilities necessary for public health laboratory (PHL) professionals to deliver the core services of PHLs efficiently and effectively. As part of a 2-year workforce project sponsored in 2012 by CDC and the Association of Public Health Laboratories (APHL), competencies for 15 domain areas were developed by experts representing state ...

For coded distributed computing (CDC), polynomial code is one prevalent encoding method for CDC (called Poly-CDC). It suffers from poor numerical stability due to the Vandermonde matrix serving as coefficient which needs be inverted, and whose condition number increases exponentially with size of or equivalently parallel worker nodes. To improve stability, especially large networks, we propose ...

Pain is a symptom common tonumerousphysical andpsychiatric ailments andcanoftenbemanagedby treating theunderlyingcondition.However, inapproximately20millionpatients eachyear,chronicpainpersistsdespitetreatment.1,2Chronicpain is complex, heterogeneous, and poorly understood. Patientswithchronicpainexperience a decreased quality of lifeandincreasedrisk formultiplecomorbidities,costingsocietybilli...

The Hospital Infection Control Practices Advisory Committee of the US Centers for Disease Control and Prevention and the National Center for Infectious Diseases have issued new isolation guidelines that replace earlier recommendations. Modifications of these guidelines for the care of hospitalized infants and children should be considered specifically as they relate to glove use for routine dia...

Affiliations: Clinical Epidemiology and Medical Statistics Unit, Dept of Biomedical Sciences – University of Sassari – Research, Medical Education and Professional Development Unit, AOU Sassari, Sassari, Italy. University of California, San Francisco, CA, USA. German Central Committee against Tuberculosis (DZK), Berlin, Germany. Institute for Global Health, University College London, London, UK...