Objectives-Synovial fluid from patients with rheumatoid arthritis contains both soluble and insoluble immunoglobulin aggregates which activate reactive oxidant production in human neutrophils. The objectives were to determine the roles played by Fc-y receptors in activation of neutrophils by these complexes. Methods-Pronase treatment was used to remove Fc-yRIII from the neutrophil surface and b...

in this study, the effects of separate and combined intraperitoneal (ip) injections of histidine and dexamethasone were investigated on local inflammation in rats. local inflammation was induced by subcutaneous (sc) injection of histamine (100 μl, 0.1%) in ventral surface of right hind paw. the thickness of paw was measured at 30 min before and 30, 60, 90, 120, 150 and 180 min after injection o...

Neutrophil surface molecules function in part as biological sensors. Surface antigens undergo several changes during neutrophilic maturation to accommodate the cell's function. Surface antigens may appear with neutrophilic maturation, such as CD16b, CD35, and CD10; disappear with maturation, such as CD49d and CD64; be maintained during maturation, such as CD32, CD59, and CD82; or disappear with...

The aim of this study was to evaluate the defense cells changes of cervical mucous during follicular and luteal phases of estrus cycle in river buffalo. Reproductive organs of the adult and apparently healthy female buffaloes were collected from the slaughterhouse. By visual investigation of both the ovaries for presence of corpus luteum and growing follicles, the luteal and follicular phase of...

hypercoagulable states are a group of conditions associated with an enhanced tendency toward blood clotting. although usual clinical manifestations of hypercoagulable states are thrombotic events such as deep venous thrombosis, hematoma can also occurs as a result of hypercoagulability in some patients. several inherited or acquired conditions may lead to hypercoagulable states. some of them in...

Dear Editor, The O2-generating enzyme NADPH oxidase, plays a crucial role in host defense against microbial infection through the production of reactive oxygen species (ROS).1The multisubunit NADPH oxidase complex can be detected in vitro by the nitroblue tetrazolium test (NBT).2The NBT test is used for the diagnosis of chronic granulomatous disease.3 However, several factors, such as some cyto...

thirty clinical cases of obstructive urolithiasis, 15 with intact urinary bladder and 15 with ruptured urinary bladder, were used to study the changes in peritoneal fluid cytology. the percentage of neutrophils was highly increased than the normal reference range reported for cattle with slight decrease in lymphocyte percentage. the value for neutrophil percent was almost similar in both intact...