Our study has investigated the level of serum apolipoprotein M (apoM) and its clinical significance in Inflammatory Bowel Disease (IBD) patients. In this study, serum apoM and tumor necrosis factor α (TNF-α) levels in newly diagnosed IBD patients (n = 101) and healthy individuals (n = 69) were measured by ELISA. Serum apoM levels in Ulcerative Colitis (UC) and Crohn’s Disease (CD) groups were f...

OBJECTIVE To evaluate and compare the sensitivity and specificity of the new serologic marker human antitissue transglutaminase antibodies (IgA anti-tTG) with those of antiendomysium (IgA EMA) and antigliadin antibodies (IgA and IgG AGA) for the diagnosis of celiac disease (CD). METHODS The level of IgA antibodies to tTG in serum was determined by an enzyme-linked immunosorbent assay (ELISA) ...

Peanut agglutinin (PNA) represents a commonly used marker for beta-type intercalated (IC) cells and their distribution in the corticomedullary course of the collecting duct (CD) in the mature rabbit kidney. It has been shown that aldosterone is able to generate >90% of PNA-binding cells in an embryonic CD epithelium in vitro. In adult kidney, a maximum of only 25% PNA-positive cells is found in...

Heat shock proteins (Hsps) are highly conserved molecular chaperones that are synthesized in response to stress. In this study, we cloned the full-length sequences of the Grp78 (glucose-regulated protein 78), Hsp70, Hsp90, and Hsp40 genes from the Chinese rice grasshopper Oxya chinensis. The full-length cDNA sequences of OcGrp78, OcHsp70, OcHsp90, and OcHsp40 contain open reading frames of 1947...

BACKGROUND In celiac disease (CD), intestinal epithelium damage occurs secondary to an immune insult and is characterized by blunting of the villi and crypt hyperplasia. Similarities between Hedgehog (Hh)/BMP4 downregulation, as reported in a mouse model, and CD histopathology, suggest mechanistic involvement of Hh/BMP4/WNT pathways in proliferation and differentiation of immature epithelial ce...

Cadmium (Cd) is a toxic heavy metal with no known biological function in plants and one of the most substances released into environment. Crops, such as rice, maize, wheat tobacco are major sources Cd for humans. toxicity inhibits crop growth development by affecting many central physiological biochemical processes, finally it affects human health via food chain. To adapt to toxicity, crops hav...

We investigated whether childhood psychopathic personality traits predicted subsequent self-reported and register-based criminality psychiatric outcomes when behavioral problems (conduct disorder [CD] ADHD symptoms) were accounted for. In the Child Adolescent Twin Study in Sweden, parents rated their children's (n = 12,394) traits, CD, symptoms at age 9/12. studied risk for delinquency, problem...

Purpose: Non-invasive tests used in the screening and follow-up of celiac disease (CD) are currently below expectations because they show false negatives/positives not always correlated with duodenal histology. We aimed to investigate predictive value intestinal free fatty acid binding protein (FABP-I) which can easily be released into circulation presence enterocyte damage a short time CD. Met...

Background The serum N-terminal telopeptide of type I collagen (NTx) is significantly higher in patients with Crohn disease (CD) than healthy individuals and ulcerative colitis. This study aimed to investigate whether an elevated NTx level a risk predictor osteoporosis CD. Methods Based on the femoral Z-score decreased over 2-year period, 41 CD were divided into ΔZ-score <0 group (Z-score de...

lymphocyte cd4 + count, a standard laboratory test for staging of hiv infection, is expensive and unavailable in resource-restricted countries. total lymphocyte count (tlc) and hemoglobin (hb) are recommended as simple & inexpensive surrogates. the aim of this study was to assess the correlation, sensitivity and predictive power of these parameters as substitutes for cd 4 count. one hundred hiv...