Methods Adult patients in need for a CVC could be included. All CVC ́s were inserted under direct in plane US guidance. After insertion US was used to screen for correct or incorrect CVC position (in the case of a CVC in the Internal Jugular Vein (IJV) the ipsilateral subclavian vein (SCV) and in case of a CVC in the SCV the ipsilateral IJV was examined. On the ipsilateral side the two upper “bl...

AIM Nerve entrapment syndromes are the most common causes of neuropathic pain. Surgical decompression is the preferred method of treatment. The aim of this study was to compare the efficacy of curcumin, tramadol and chronic constriction release treatment (CCR), individually or together, in a rat model of sciatic nerve injury. MATERIAL AND METHODS Eighty male rats were divided into eight study...

A preliminary version of this work appeared as [2]. y Supported in part by National Science Foundation grant CCR-9000045. Some of this research was performed while the author was a visiting professor at Institut f ur Informatik, Universit at W urzburg, D-8700 W urzburg, Federal Republic of Germany. z Supported in part by the National Science Foundation grants CCR-8808949 and CCR-8958528. Wo...

Stevens et al suggest that the Modification of Diet in Renal Disease (MDRD) Study equation for estimated glomerular filtration rate (GFR) is an acceptable substitute for estimated or measured creatinine clearance (CCr) as an index for adjusting drug doses in patients with chronic kidney disease and acute kidney injury. However, others have raised concerns that injudicious use of estimated GFR a...

Abstract: The radial measures of classical DEA models (CCR, BCC) are incomplete, they are only separate measures of input and output efficiency and their efficiency index omit the non-zero input and output slacks. Enhanced Russell graph measure (ERM) eliminates these deficiencies. All of the existing fuzzy DEA models are extension of CCR or BCC model, efficiencies of DMUs, ultimately, are solut...

A major obstacle to presymptomatic diagnosis and disease-modifying therapy for Alzheimer's disease (AD) is inadequate understanding of molecular mechanisms of AD pathogenesis. For example, impaired brain insulin signaling is an AD hallmark, but whether and how it might contribute to the synaptic dysfunction and neuron death that underlie memory and cognitive impairment has been mysterious. Neur...

Methicillin-resistant Staphylococcus aureus (MRSA) has been a major cause of nosocomial infection in Irish hospitals for 4 decades, and replacement of predominant MRSA clones has occurred several times. An MRSA isolate recovered in 2006 as part of a larger study of sporadic MRSA exhibited a rare spa (t878) and multilocus sequence (ST779) type and was nontypeable by PCR- and DNA microarray-based...

Can creatinine clearance in children clear the indexing GFR with BSA from the charge of errors? We read with interest the article of Delanaye and colleagues stating that indexing glomerular filtration rate (GFR) with body surface area (BSA) required mathematical prerequisites to be satisfied, even though many studies reported they were not [1]. Although not the gold standard to measure GFR, cre...

The pharmacokinetics of netilmicin were examined in 25 adult subjects, 7 normal subjects, and 18 patients with renal impairment. Five were dialysis patients who were studied on and off dialysis. Netilmicin, 2 mg/kg, was infused intravenously over 1 h. The peak serum concentration ranged from 9 to 11 mug/ml. The mean biological half-life of netilmicin for subjects with a creatinine clearance (Cc...