Enhancers and promoters assemble protein complexes that ultimately regulate the recruitment and activity of RNA polymerases. Previous work has shown that at least some enhancers form stable protein complexes, leading to the formation of enhanceosomes. We analyzed protein-DNA interactions in the murine β-globin gene locus using the methyltransferase accessibility protocol for individual template...

[1] A new magnetic map of the Moon, based on Lunar Prospector magnetometer observations, sheds light on the origin of the South Pole-Aitken basin (SPA), the largest and oldest of the recognized lunar basins. A set of WNW-trending linear to arcuate magnetic features, evident in both the radial and scalar observations, covers much of a 1000 km wide region centered on the NW portion of SPA. The so...

KREEP materials were thought to be last crystallized at the lunar crust and mantle boundary. Impact cratering and volcanism are mainly responsible for their distributions on the lunar surface. Therefore, observation of global KREEP materials and investigation of distributions in the areas of large basins are of critical importance to understand the geologic history of the Moon. Here we report t...

The mare exhibits nocturnal uterine contractions in the last 6 days of gestation. It is hypothesized that estradiol 17beta (O17beta) may be associated with the nightly increase in uterine contractions. The 24-h secretion pattern of plasma O17beta was measured in 3 pony mares in late gestation to identify changes in release as the mare neared parturition. Blood was collected weekly at 08:00 hour...

Origin of Lunar Basalts: A Geophysical Interpretation J. Arkani-Hamed Lunar Pyroclastic Soils of the Apollo 17 Double Drive Tube 74001/2 A. Basu, D. S. McKay, and S. J. Wentworth Lunar Explosive Volcanism: The Remote Sensing Perspective C. R. Coombs and B. R. Hawke The Optimal Lunar Resource: Ilmenite-rich Regional Pyroclastic Deposits C. R. Coombs, B. R. Hawke, and B. Clark Pyroclastic Volcani...

The mare ovary is unique in its anatomical structure; however, the signalling pathways responsible for physiological processes, such as follicular activation, remain uncharacterised. This provided us with the impetus to explore whether signalling molecules from important folliculogenesis pathways, phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) and Janus kinase/signal transducer and activ...

Objective: This prospective study aims to compare three different sampling techniques for the collection of endometrial cytological specimens in the mare: the guarded culture swab, the uterine cytobrush and the low volume uterine flush. Material and methods: The study po pulation consisted of six healthy Standardbred mares in dioestrus. In each mare an acute endometritis was induced by performi...

induced abortion may be desired during a normal or abnormal pregnancy. the methods of induced abortion differ between species mainly because of different sources for progesterone production during pregnancy between species and within a species according to different stages of gestation. in cows and buffaloes, pregnancy can be effectively terminated from 5 to 150 days by administration of luteol...

anti-müllerian hormone (amh) has been observed to decrease with the development of hemorrhagic anovulatory follicles (hafs) in mares. two studies were conducted to evaluate amh concentration in mares with hafs compared to seasonally anoestrous and cyclic mares, and to elucidate changes of amh with the development of luteinised unruptured follicles (lufs). in study 1, amh and progesterone were e...

Mare domes, small shield volcanoes typically <∼30 km diameter, are part of the spectrum lunar volcanic features that characterize extrusive basalt deposits. We used new spacecraft data to document these in Tranquillitatis, among oldest maria and site commonly interpreted as an ancient degraded non-mascon impact basin. found 283 known suspected mare with majority (n = 229) concentrated on a broa...