the purpose of the present study was to compare the effects of one- and two-session(s)-per-week training programs on musculoskeletal and cardiovascular indices in sedentary female university students. 111 voluntary sedentary female university students were randomly divided into three groups (one session groups (os): n=37, mean age 21.02±1.73 years, two sessions group (tn): n=35, mean age 21.17±...

INTRODUCTION Exercise reduces arterial and central venous blood pressures during recovery, which contributes to its valuable anti-hypertensive effects and to facilitating hypervolemia. Repeated sprint exercise potently improves metabolic function, but its cardiovascular effects (esp. hematological) are less well-characterized, as are effects of exercising upper versus lower limbs. The purposes ...

Background: Greater aerobic fitness is associated with improved cardiovascular health. Traditionally high volume (long duration and low intensity) endurance training (ET) has been used to increase aerobic fitness. Sprint interval training (SIT) is a low volume and high intensity form of interval training. Energy for SIT is produced via both the aerobic and anaerobic metabolic pathways. SIT is t...

1-Methylnicotinamide (MNA), which was initially considered to be a biologically inactive endogenous metabolite of nicotinamide, has emerged as an anti-thrombotic and anti-inflammatory agent with the capacity to release prostacyclin (PGI2). In the present study, we characterized the effects of MNA on exercise capacity and the endothelial response to exercise in diabetic mice. Eight-week-old db/d...

Successful completion of endurance exercise is facilitated by conditioning that enhances the capacity of the cardiovascular and musculoskeletal systems to maintain a high level of aerobic activity. Insufficiency or disease in these systems may be diagnosed using routine haematology and serum chemistry testing. Pre-race blood samples obtained from 82 endurance-trained sled dogs were used to test...

Statins are cholesterol-lowering drugs widely used in the prevention of cardiovascular diseases; however, they are associated with various types of myopathies. Statins inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase and thus decrease biosynthesis of low-density lipoprotein cholesterol and may also reduce ubiquinones, essential coenzymes of a mitochondrial electron transport ch...

Intellectual disability (ID) and living in residential home settings may be a disadvantage for an active lifestyle and healthy aging. The purpose of this study was to determine physical fitness (PF) levels of women with mild intellectual disabilities (n=31; mean age 22.22±3.11 years), clients of residential homes, and to compare them to the PF levels of their control peers (n=31; 23.16±3.12 yea...

Loss of physical performance is linked not only to decreased activity in daily life but also to increased onset of cardiovascular diseases and mortality. A high-protein diet is recommended for aged individuals in order to preserve muscle mass; however, the regulation of muscle mitochondria by dietary protein has not been clarified. We investigated the long-term effects of a high-protein diet on...

Normally, central elastic arteries (e.g., aorta and common carotid artery) effectively buffer cardiac pulsation-induced flow/pressure fluctuations. With advancing age, arterial stiffening deteriorates this function and produces the greater cerebral hemodynamic pulsatility that impacts vulnerable brain tissue. It is well known that the buffering function of the central artery is improved by regu...