نتایج جستجو برای: cardiac glycosides
تعداد نتایج: 282550 فیلتر نتایج به سال:
The widely accepted model to explain the positive inotropic effect of cardiac glycosides invokes altered Na+-Ca2+ exchange activity secondary to Na+ pump inhibition. However, proof of this model is lacking and alternative mechanisms have been proposed. We directly tested the role of the Na+-Ca2+ exchanger in the action of the glycoside ouabain using Na+-Ca2+ exchanger knockout mice. Ablation of...
The induction of apoptosis by 66 alkaloids of the quinoline, quinolizidine, pyrrolizidine, isoquinoline, indole, terpene, tropane, steroid, purine, and piperidine type, of 9 cardiac glycosides, 11 non-protein amino acids and 10 further secondary metabolites was assayed in HL-60 cell cultures and measured by quantification of the subdiploid DNA content by flow cytometry, detection of DNA fragmen...
After administration of sodium fl —14C]acetate to rhizome or root cuttings of Convallaria maja lis L. two of the main cardiac glycosides were isolated and examined for incorporated radioactivity. With a detection limit of 0.0003% of incorporated label it can be assumed, that the subterranean organs o f C. majalis are not capable of cardenolide biogenesis de novo. Interconversions on the carden...
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