coronary risk factors and use of statins with progression of mild valvular aortic stenosis in older persons. Am J Cardiol 2001;88:693–5. 12. Novaro GM, Tiong IY, Pearce GL, Lauer MS, Sprecher DL, Griffin BP. Effect of hydroxymethylglutaryl coenzyme A reductase inhibitors on the progression of calcific aortic stenosis. Circulation 2001;104: 2205–9. 13. Bellamy MF, Pellikka PA, Klarich KW, Tajik ...

ARMOUR, J. A., AND W. C. RANDALL. Structural basis for cardiac function. Am. J. Physiol. 218(6): 1517-1523. 1970.-In nine species of,mammals, anatomic evaluation of fresh specimens demonstrated that the ventricles of the heart are grossly structured as a continuum of muscle strands. These strands originate and insert into a basal fibrous skeleton consisting of four interconnected, triangular ac...

Both right and left ventricles are developed from two adjacent segments of the primary heart tube. Though they are different with regard to shape and power, they mirror each other in terms of behavior. This is the first level of symmetry in cardiac function assessment. Both cardiac muscle contraction and relaxation are active. This constructs the second level of symmetry in cardiac function ass...

Sixteen healthy men were evaluated for left ventricular performance changes and fl-blockade after therapeutic oral doses of disopyramide and propranolol administered alone and concurrently. The volunteers were randomly assigned to receive one of two drug treatment regimens that differed in the sequence and duration of administration of the dmgs. Left ventricular function was assessed by echocar...

At present no clear-cut physiologic/serological parameter exist which enable an early identification of neonates who are at increased risk to develop myocardial dysfunction in perinatal asphyxia. This study was conducted to find out the incidence and features of cardiac dysfunction in perinatal asphyxia The present study was carried out on 48 neonates ,17 healthy neonates were taken as controls...

Introduction: Roux-en-Y gastric bypass (RYGB) reduces weight and long-term cardiovascular risk in obese patients. We showed that endothelial-mediated vasorelaxation improves rapidly in diet-induced obese (DIO) rats within 8 days after RYGB and is associated with reduced activation of JNK independently from weight loss. Purpose: We investigated whether in vivo inhibition of JNK with two differen...

conclusions silent ventricular systolic dysfunction was more common in the patients with sle than in the control group. newer echocardiographic techniques such as two-dimensional ste provide an earlier chance for the detection of subclinical lv systolic dysfunction. our findings were independent of the traditional risk factors. results the mean duration of sle was 5.5 ± 3.4 years in our patient...

Proper generation and conduction of the cardiac electrical impulse is essential for the continuous coordinated contraction of the heart. Dysregulation of cardiac electrical function may lead to cardiac arrhythmias, which constitute a huge medical and social burden. Identifying the genetic factors underlying cardiac electrical activity serves the double purpose of allowing the early identificati...

Abstract Objectives This study was designed to evaluate echocardiographic findings in patients with obstructive sleep apnea (OSA) cognitive impairment and compare it the control group. Methods Sixty-seven OSA 52 group of healthy controls were evaluated prospectively by Mini-Mental State Examination questionnaire trans-thoracic echocardiography. Results The diastolic dysfunction 19.6% ( P = .002...

Objective(s): Diabetic cardiomyopathy is a leading factor of high morbidity and mortality in diabetic patients. Our previous results revealed that ginkgolide B alleviates endothelial dysfunction in diabetic rats. This study aimed to investigate the effect of ginkgolide B on cardiac dysfunction and its mechanism in diabetic rats.Materials and Methods:<...