Introduction. The high level of environmental pollution in industrial cities, including carcinogens, causes an unacceptable risk to public health. In this regard, a quantitative assessment is required develop preventive measures reduce it. aim the study was assess carcinogenic health population industrialized city, caused by probable presence carcinogens ambient air, drinking water centralized ...

Work in leather tanning involves exposure to a wide range of chemicals. Some of these are carcinogens or suspected carcinogens. Increased risks for a number of cancers have been reported among the tannery workers. In the present review, a detailed account of lung cancer, testicular cancer, soft tissue sarcoma, pancreatic cancer, bladder cancer among tannery workers is mentioned.

Drug-metabolizing enzymes are called mixed-function oxidase or monooxygenase and containing many enzymes including cytochrome P450, cytochrome b5, and NADPH-cytochrome P450 reductase and other components. The hepatic cytochrome P450s (Cyp) are a multigene family of enzymes that play a critical role in the metabolism of many drugs and xenobiotics with each cytochrome isozyme responding different...

In the analysis by Parry et al. [Parry, J. M., Parry, E., Phrakonkham, P. and Corvi, R. (2010) Analysis of published data for top concentration considerations in mammalian cell genotoxicity testing. Mutagenesis, 25, 531-538], 24 rodent carcinogens that were negative in the Ames test were identified that were only positive in mammalian cell tests at concentrations between 1 and 10 mM. These carc...

Cancer is one of the critical health concerns. Health authorities around world have devoted great attention to cancer and causing factors achieve control against increasing rate cancer. Carcinogens are most salient that accused a considerable cases. Scientists, in different fields knowledge, keep warning people imminent attack carcinogens which surrounding environment may launch their at any mo...