نتایج جستجو برای: calorie restriction

تعداد نتایج: 78389  

Journal: :Cell 2008
Leonard Guarente

Recent studies of calorie restriction in several organisms demonstrate an increase in mitochondrial activity that is associated with the salutary effects of this dietary restriction regimen. In this Essay, I speculate on how an increase in mitochondrial activity might provide benefit and discuss how diet, mitochondria, and sirtuins might interact in a pathway to slow aging and associated diseases.

2017
Yoshiro Naito Aya Senchi Hisashi Sawada Makiko Oboshi Tetsuo Horimatsu Keisuke Okuno Seiki Yasumura Masaharu Ishihara Tohru Masuyama

BACKGROUND We have previously shown that dietary iron restriction prevents the development of renal damage in a rat model of chronic kidney disease (CKD). However, iron deficiency is associated with appetite loss. In addition, calorie restriction is reported to prevent the development of end-stage renal pathology in CKD rats. Thus, the beneficial effect of iron restriction on renal damage may d...

Journal: :Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 2008

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