An oxime based fluorescent probe has been designed and synthesized, which detects free as well as enzymatically generated hypochlorite with a low detection limit and high sensitivity. In addition, the probe was successfully utilized for the monitoring of endogenously produced hypochlorite in LPS stimulated cell lines, C6 glioma and BV2 microglia.

The use of different concentrations of sodium hypochlorite solutions (placebo; 1% and 3.5% sodium hypochlorite solutions) and 2 water-storage containers (traditional plastic container and the improved CDC safe water-storage container) as interventions in 2 rural communities using different water sources (improved vs. unimproved) was evaluated over a period of 4 months. Standard methods were use...

This study evaluated heat-polymerized (HPR) and microwave-polymerized acrylic resins (MPR), after immersion in water, 1% hypochlorite and Ricinus communis solution (RC). Knoop hardness, color alteration, roughness and flexural strength tests were performed after obtaining the specimens and after time intervals of 15 (T) and 183 (T) days. Variations in data (∆) were submitted to ANOVA and Tukey ...

Objective: To evaluate the effect of socially marketed faucet fitted to earthen vessel / sodium hypochlorite solution on diarrhea prevention at rural household level as a social intervention for diarrhea prevention under ‘Community Led Initiatives for Child Survival (CLICS) program. Methods: Unmatched case-control study was carried out in 10 villages of Primary Health Centre, Anji, located in r...

STUDY OBJECTIVE Neutrophils are involved in acute lung injury during ARDS via several mechanisms. This study focuses on neutrophil-derived oxidative stress. Hypochlorite is a major neutrophil-derived oxidant. This study characterizes hypochlorite-induced acute changes in pulmonary circulation and the involvement of tissue lipid peroxidation (LPO) and reduced glutathione (rGSH) depletion. METH...

OBJECTIVE Disinfection procedures often cause deterioration in a maxillofacial prosthesis. Color and hardness alterations could lead to a replacement of the prosthesis. MATERIAL AND METHODS An experimental chlorinated polyethylene (CPE) and a commercial polydimethyl siloxane (PDMS) sample were treated with four different disinfection procedures for a period which simulates 1 year of clinical ...

Sodium hypochlorite is widely used as an irrigating solution in dental practice. Despite its safe properties, serious complications can result from inadvertent use. We report a patient presenting to the accident and emergency department for sodium hypochlorite accident during dental root canal therapy. The management of this dental emergency condition is discussed. (Hong Kong j.emerg.med. 2010;...

The benefits of using sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) as endodontic irrigants, and calcium hydroxide as an inter-appointment medicament, are well known to dentists. Many steps undertaken during endodontic treatment and retreatment are rather mechanical in nature, and less attention is committed to understanding the biological issues underlying endodontic t...

An alkaline agent, namely food additive grade calcium hydroxide (FdCa(OH)2) in solution at 0.17%, was evaluated for its bactericidal efficacies in chiller water with sodium hypochlorite (NaOCl) at a concentration of 200 ppm total residual chlorine. Without organic material presence, NaOCl could inactivate Salmonella Infantis and Escherichia coli within 5 sec, but in the presence of fetal bovine...

Inflammatory periapical lesions are one of the major complications of dental injuries. Here we report a case of large cyst-like periradicular lesion from the apices of 31, 41, 42 in an 18-yr-old boy that was managed by using nonsurgical and surgical endodontic methods. During endodontic procedure, 2.5 % sodium hypochlorite solution was used for irrigation and calcium hydroxide paste was used fo...