The title compound, C(11)H(12)ClNO(4)S, adopts a Z configuration about the C=C double bond. The benzisothia-zole system is essentially planar [maximum deviation of 0.235 (2) Å for the S atom]. In the crystal, the mol-ecules stack parallel to each other in the b-axis direction, with inter-planar spacings for the benzene and thia-zole rings ranging from 3.402 (2) to 3.702 (2) Å.

The aim of this study was to investigate the antimicrobial activity of calcium hydroxide (Ca(OH)2) combined with 2% chlorhexidine gluconate (CHX) gel against endodontic pathogens and to compare the results with the ones achieved by Ca(OH)2 mixed with sterile water and by CHX gel alone. Two methods were used: the agar diffusion test and the direct contact test. Ca(OH)2 + 2% CHX gel produced inhi...

The Escherichia coli gntT gene was subcloned from the Kohara library, and its expression was characterized. The cloned gntT gene genetically complemented mutant E. coli strains with defects in gluconate transport and directed the formation of a high-affinity gluconate transporter with a measured apparent Km of 6 microM for gluconate. Primer extension analysis indicated two transcriptional start...

The metabolism of gluconate is well characterized in prokaryotes where it is known to be degraded following phosphorylation by gluconokinase. Less is known of gluconate metabolism in humans. Human gluconokinase activity was recently identified proposing questions about the metabolic role of gluconate in humans. Here we report the recombinant expression, purification and biochemical characteriza...

Familial isolated hypoparathyroidism (FIH) is a rare group of genetic disorder associated with dysregulation parathyroid hormonal axis characterized by refractory hypocalcaemia. Herein we report 1 month 4 days old baby born out consanguineous marriage presented respiratory distress single episode convulsion, cause pointing towards The hypocalcaemia symptoms were despite repeated calcium glucona...

statement of the problem: a major objective of investigators is to clarify the role of metabolites in achievement of maximum tooth movement with minimal root damage during orthodontic tooth movement (otm). purpose: the aim of this study was to determine the effect of administration of thyroid hormone, prostaglandin e2, and calcium on orthodontic tooth movement and root resorption in rats. mater...

BACKGROUND For patients unable to receive heparin anticoagulation during haemodialysis, saline flushes to reduce circuit clotting are often the norm. Regional citrate anticoagulation (RCA) although effective is not used by many centres including in Singapore. We wanted to demonstrate the superiority and safety of a simple regional citrate anticoagulation regime, compared to saline flushes, for ...

The aim of this in vitro study was to evaluate enamel microhardness following bleaching treatments using either high- or low-concentration hydrogen peroxide (HP) agents containing calcium and/or fluoride. Sixty enamel blocks were bleached with 1 of 6 different bleaching agents (n = 10). The high-concentration HP agents were Whiteness HP Maxx (35% HP), Whiteness HP Blue (35% HP, 2% calcium gluco...

We experienced a case of familial hypoparathyroidism with an autosomal dominant pattern of transmission and performed molecular analysis of the calcium-sensing receptor (CASR) gene. The patient was a female neonate, born by cesarean section at term because of breech presentation. Her mother had been diagnosed with idiopathic hypoparathyroidism at the age of 9 yr and had been receiving vitamin D...