Midkine (MK; a low molecular weight heparin-binding growth factor) is a multifunctional cytokine. MK plays a role in morphogenesis of many organs including teeth through epithelial-mesenchymal interactions. We immunohistochemically examined MK expression in various human odontogenic tumors. There was no difference in positive rate and intensity of MK between benign odontogenic tumors and their ...

Ghost cells have been a topic of controversy since a long time. The appearance of these cells in different lesions has given it varying terms. In lesions like that of Calcifying cystic odontogenic tumor (CCOT), these cells have been termed as 'Ghost cells' whereas similar descriptive cells have been called shadow/translucent cells in non-odontogenic lesions like Craniopharyngiomas of the pituit...

background. the aim of this study was to investigate myofibroblast (mf) density in a broad spectrum of odontogenic cysts and tumors and the relation between the density of mfs and the clinical behavior of these lesions. methods. a total of 105 cases of odontogenic lesions, including unicystic ameloblastoma (uam), solid ameloblastoma (sa), odontogenic keratocyst (okc), dentigerous cyst (dc), rad...

OBJECTIVES Since its recognition as a physiologic process associated with tumor, among molecular mechanisms involved in tumor progression, defects in regulation of apoptosis have generated an accelerating volume of research that has sought to elucidate the role of programed cell death in pathogenesis and treatment of various tumors. Therefore, this study was performed to understand better the d...

Introduction: squamous odontogenic tumor is a rare benign locally infiltrative odontogenic tumor of epithelial origin and only a few cases, less than 50, have been reported in literature. the challenge is in diagnosing the tumor is due to its close resemblance to acanthomatous ameloblastoma and well differentiated squamous cell carcinoma. case report: Herein we report, not previously reported, ...

Background. The aim of this study was to investigate myofibroblast (MF) density in a broad spectrum of odontogenic cysts and tumors and the relation between the density of MFs and the clinical behavior of these lesions. Methods. A total of 105 cases of odontogenic lesions, including unicystic ameloblastoma (UAM), solid ameloblastoma (SA), odontogenic keratocyst (OKC), dentigerous cyst (DC), rad...

BACKGROUND The purpose of the study was to correlate the provisional diagnosis of pericoronal radiolucencies associated with impacted, embedded, or unerupted teeth with the histopathologic diagnosis, and also to emphasize the importance of early detection for better diagnosis and management. METHODS This is a retrospective study involving 18 cases of pericoronal radiolucencies associated with...