نتایج جستجو برای: c3 paradigm

تعداد نتایج: 120396  

Purpose: The present work aimed to find out if the concept of paradigm in Tomas Kuhn’s Philosophy has any equivalents in the area of Library and Information Science (LIS). Methodology: After a comprehensive study of the book “The Structure of Scientific Revolutions”, especially the concept of paradigm in it, the LIS related theories are critically investigated and recommendations on the necess...

Journal: :Developmental and comparative immunology 2009
Maria G Castillo Michael S Goodson Margaret McFall-Ngai

Examination of the EST database of the light organ of the Hawaiian bobtail squid Euprymna scolopes revealed a sequence with similarity to complement C3. RACE yielded the full open reading frame of this protein. Analysis of the resultant sequence revealed that Es-C3 (E. scolopes-C3) has conserved residues and domains known to be critical for C3 function. The gene encoding C3 was expressed in all...

Journal: :The Journal of Experimental Medicine 1974
M. B. Pepys

In an in vivo study in mice, suppression by the C3-cleaving protein of cobra venom (CoF), and other C3-reactive agents (zymosan, aggregated IgG, anti-C3 antibodies, and type III pneumococcal polysaccharide) of the thymus-dependent antibody responses to sheep erythrocytes, ovalbumin, and human IgG was demonstrated. The thymus-independent antibody response to polyvinyl-pyrrolidone was however una...

Journal: :The Journal of Experimental Medicine 1974
Argyrios N. Theofilopoulos Viktor A. Bokisch Frank J. Dixon

This study describes the presence of a receptor for fluid phase human C3 and C3b on Raji cell membranes. The binding of C3 and C3b was demonstrated indirectly by a fluoresceinated anti-C3 serum and directly by using radioiodinated proteins. No other complement proteins or serum factors were needed to mediate binding of C3 and C3b to the receptor. The possibility of enzymatic cleavage of C3 befo...

Journal: :European heart journal 2000
A Muscari G Massarelli L Bastagli G Poggiopollini V Tomassetti G Drago C Martignani P Pacilli P Boni P Puddu

AIMS Serum C3 is a powerful indicator of the risk of myocardial infarction, which correlates with body mass index, serum lipids and blood pressure. This study was performed to ascertain whether such correlations may be explained by an association of C3 with fasting insulin, and to assess comparatively the relationships of C3 and traditional risk factors to previous myocardial infarction. METH...

Journal: :Infection and immunity 2009
Vishakha Sabharwal Sanjay Ram Marisol Figueira In Ho Park Stephen I Pelton

Strategies to limit complement deposition on Streptococcus pneumoniae are established as virulence features for invasive disease, but their role in respiratory tract infection requires further analysis. We evaluated complement C3 protein deposition on discordant S. pneumoniae isolates of the same serotype (6A) and their capacity to cause nasopharyngeal (NP) colonization and experimental otitis ...

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