The effect of minor additions substitutional elements such as Al, Cu, Mn, and Fe on the room-temperature (RT) elevated-temperature hardness a single bcc phase Hf20Nb31Ta31Ti18 refractory high entropy alloy is studied here. Interestingly, 2.5 at. % nominal addition hardened base in temperature range from RT to 800 °C, while same content Mn softened 1000 °C. Regardless solid solution hardening or...

results using these two sets, we identified h1069q mutation in four patients, c.2335t > g mutation in three, c.3061-1g > a splice site mutation in five, c.3305t > c mutation in one, and c.3809a > g mutation in two patients. conclusions the multiplex arms assay used in this study can be an efficient, reliable, and cost effective method as a primary screen for patients with wilson disease. patien...

Pyridoxine-dependent epilepsy presents early in life, even in utero. It is usually refractory to conventional antiepileptic medications and responds only to lifelong pyridoxine supplementation. Seizures are usually generalized tonic clonic. We report a 3-year-old child that was born prematurely at 25 weeks of gestation. He presented with abnormal movements in the second month of life. At 10 mon...

objective epilepsy occurs with a yearly incidence of 40 per 100,000 children, of which more than 25% are resistant to drug therapy. epilepsy may occur in autoimmune diseases like lupus, celiac disease and myasthenia gravis. in this study, the relationship between celiac disease and refractory epilepsy was evaluated in children with idiopathic epilepsy. material & methods hundred-fifty-five chil...

objective 1-3% of the population suffer from epilepsy. up to 30% of them develop refractory epilepsy and their seizures occur more than once per month despite receiving at least 2 first line antiepileptic drugs. in  this group, more efficacious antiepileptics are needed. this study was undertaken to evaluate the efficacy and safety of oxcarbazepine as an adjunction therapy in children with refr...

This work has studied the possibility of purifying termite hill clay hydrometallurgically and subsequently adapting it for furnace lining by the addition of graphite and rice husk granules. A large quantity of termite hill clay was mined from a location on the campus of The Federal University of Technology, Akure (FUTA), Nigeria. The slurry obtained from the clay after washing in water was sund...

We welcome the opportunity to respond to the Comment of Bence et al. (2000) regarding the suitability of the new geochemical parameter we have introduced. Part of their comment, however, addresses issues either not directly related to our paper, or issues published elsewhere. The lengthy comment seems a disproportionate reaction to what was a paper of limited scope, simply introducing one new g...

Objective(s):Organic anion transporter polypeptide 1B1 (OATP1B1) encoded by solute carrier organic transporter 1B1 (SLCO1B1) gene; a transporter involved in the uptake of drugs and endogenous compounds is present in hepatocyte sinusoidal membrane. Aim of this study was to investigate the frequencies of functionally significant SNPs (388A>G and 521T>C) and their haplotypes in 6 ethnic groups of ...

Background and aim: Treatment of resistant warts is a common clinical problem. Immunotherapy with diphenyl cyclopropenone (DCP) as a contact sensitizer has been reported. The objective of this study was to evaluate the efficacy of DCP in refractory warts.Materials and methods: Nineteen patients with refractory warts referred to Razi Hospital in 2004 who had not responded to at least 2 treatment...