Two simple, rapid and inexpensive methods based on spectrophotometry and turbidimetry have been developed for the determination of cyproheptadine hydrochloride (CPH) in pure form and in dosage forms with Bromophenol Blue (BPB) as the reagent. The spectrophotometric method is based on the formation of an ion-pair complex between the drug and BPB in an acidic buffer. The ion-pair complex formed, ...

the purpose of this study was to design and optimize an oral controlled release acyclovir mucoadhesive tablet, in term of its drug release and mucoadhesive strength. a 32 full factorial design was employed to study the effect of independent variables like carbopol-934p and hydroxypropyl methylcellulose k100m, which significantly influence characteristics like swelling index, ex-vivo mucoadhesiv...

Controlled-release formulations (CRFs) have potential applications in modern agriculture, for it can not only prolong the duration of agrochemicals but also alleviate adverse effect on non-targ...

This paper considers the Red-Blue Transportation Problem (Red-Blue TP), a generalization of the transportation problem where supply nodes are partitioned into two sets and socalled exclusionary constraints are imposed. We encountered a special case of this problem in a hospital context, where patients need to be assigned to rooms. We establish the problem’s complexity, and we compare two intege...

Controlled release tablets containing 50 mg diclofenac sodium (DS) and 40% mastic with other natural additives were prepared. Drug release was examined and stability was studied using non-isothermal and isothermal thermogravimetric analysis (TGA). The bioavailability of two controlled release tablet formulations was studied and compared to that of commercial tablets, and rabbit stomachs were al...

In buildings growing conditions for mould fungi can occur and cause fungus infestation. The possible danger for the occupants of dwellings lies in the production and spreading of pathogens (disease causing agents). Therefore, consequent measures have to be taken to avoid health dangers that result from mould fungi in buildings. A strategy has to be set up that focuses on the growth conditions f...

Objectives: To evaluate the amnion graft in vaginoplasty, to assess the advantage of a flap placed over fourchette and to evaluate the benefit of gauze mould. Methods: Out of the 35 subjects of primary amenorrhea, eight with complete vaginal agenesis were selected for vaginoplasty. Half of these received split thickness skin graft and other half received amnion graft. An additional triangular f...

Nano-delivery systems for the active ingredients of pesticides can improve the utilization rates of pesticides and prolong their control effects. This is due to the nanocarrier envelope and controlled release function. However, particles containing active ingredients in controlled release pesticide formulations are generally large and have wide size distributions. There have been limited studie...

Several application parameters of microencapsulated (MEC) sex pheromone formulations were manipulated to determine their impact on efficacy of disruption for codling moth, Cydia pomonella (L.); oriental fruit moth, Grapholita molesta (Busck); obliquebanded leafroller, Choristoneura rosaceana (Harris); and redbanded leafroller, Argyrotaenia velutinana (Walker). Depending on the experiment, the f...